Holler involves a family anchored by a brother named Blaze (Gus Halper) and a sister named Ruth (Jessica Barden). They live in a Southern Ohio town that is slowly dying, with no jobs and no future. Ruth is a math whiz, so much so that Blaze convinces her to apply to college, and she’s accepted. But Ruth is also conflicted about leaving, having begun a new job with Blaze collecting scrap metal – often stolen from from local shutdown factories – and not wanting to abandon her mother (Pamela Adlon), who is doing time in drug rehab. Will Ruth stay or will she go now?