Sort by Popularity - Most Popular Movies and TV Shows tagged with keyword "anti-depressant"

1. Two and a Half Men (2003–2015)

TV-14 | 22 min | Comedy, Romance

A hedonistic jingle writer's free-wheeling life comes to an abrupt halt when his brother and 10-year-old nephew move into his beach-front house.

Stars: Jon Cryer, Ashton Kutcher, Angus T. Jones, Conchata Ferrell

Votes: 281,980

2. Homeland (2011–2020)

TV-MA | 60 min | Crime, Drama, Mystery

A bipolar CIA operative becomes convinced a prisoner of war has been turned by al-Qaeda and is planning to carry out a terrorist attack on American soil.

Stars: Claire Danes, Mandy Patinkin, Damian Lewis, Rupert Friend

Votes: 362,890

3. Children of Men (2006)

R | 109 min | Action, Drama, Sci-Fi

In 2027, in a chaotic world in which women have somehow become infertile, a former activist agrees to help transport a miraculously pregnant woman to a sanctuary at sea.

Director: Alfonso Cuarón | Stars: Julianne Moore, Clive Owen, Chiwetel Ejiofor, Michael Caine

Votes: 532,324 | Gross: $35.55M

4. Love & Other Drugs (2010)

R | 112 min | Comedy, Drama, Romance

In 1990s Pittsburgh, a medicine peddler starts a relationship with a young woman suffering from Parkinson's disease.

Director: Edward Zwick | Stars: Jake Gyllenhaal, Anne Hathaway, Judy Greer, Oliver Platt

Votes: 225,415 | Gross: $32.37M

5. The Empty Man (2020)

R | 137 min | Drama, Horror, Mystery

On the trail of a missing girl, an ex-cop comes across a secretive group attempting to summon a terrifying supernatural entity.

Director: David Prior | Stars: James Badge Dale, Marin Ireland, Sasha Frolova, Samantha Logan

Votes: 38,787

6. Amy (III) (2015)

R | 128 min | Documentary, Biography, Music

Archival footage and personal testimonials present an intimate portrait of the life and career of British singer/songwriter Amy Winehouse.

Director: Asif Kapadia | Stars: Amy Winehouse, Mitch Winehouse, Mark Ronson, Russell Brand

Votes: 55,385 | Gross: $8.41M

7. Dolores Claiborne (1995)

R | 132 min | Crime, Drama, Mystery

A big city reporter travels to a small town where her mother has been arrested for the murder of an elderly woman for whom she worked as a housekeeper.

Director: Taylor Hackford | Stars: Kathy Bates, Jennifer Jason Leigh, Christopher Plummer, Judy Parfitt

Votes: 48,643 | Gross: $24.36M

8. Possessor (2020)

R | 103 min | Horror, Mystery, Sci-Fi

An agent works for a secretive organization that uses brain-implant technology to inhabit other people's bodies - ultimately driving them to commit assassinations for high-paying clients.

Director: Brandon Cronenberg | Stars: Andrea Riseborough, Christopher Abbott, Jennifer Jason Leigh, Rossif Sutherland

Votes: 45,965

9. Michael Clayton (2007)

R | 119 min | Crime, Drama, Mystery

A law firm brings in its "fixer" to remedy the situation after a lawyer has a breakdown while representing a chemical company that he knows is guilty in a multibillion-dollar class action suit.

Director: Tony Gilroy | Stars: George Clooney, Tilda Swinton, Tom Wilkinson, Michael O'Keefe

Votes: 175,049 | Gross: $49.03M

10. Side Effects (I) (2013)

R | 106 min | Crime, Drama, Mystery

A young woman's world unravels when a drug prescribed by her psychiatrist has unexpected side effects.

Director: Steven Soderbergh | Stars: Rooney Mara, Channing Tatum, Jude Law, Catherine Zeta-Jones

Votes: 198,227 | Gross: $32.17M

11. Another Earth (2011)

PG-13 | 92 min | Drama, Mystery, Romance

On the night of the discovery of a duplicate Earth in the Solar system, an ambitious young student and an accomplished composer cross paths in a tragic accident.

Director: Mike Cahill | Stars: Brit Marling, William Mapother, Matthew-Lee Erlbach, DJ Flava

Votes: 100,624 | Gross: $1.32M

12. Submarine (2010)

R | 97 min | Comedy, Drama, Romance

15-year-old Oliver Tate has two objectives: to lose his virginity before his next birthday, and to extinguish the flame between his mother and an ex-lover who has resurfaced in her life.

Director: Richard Ayoade | Stars: Craig Roberts, Sally Hawkins, Paddy Considine, Noah Taylor

Votes: 97,086 | Gross: $0.47M

13. Grizzly Man (2005)

R | 103 min | Documentary, Biography

A devastating and heart-rending take on grizzly bear activists Timothy Treadwell and Amie Huguenard, who were killed in October of 2003 while living among grizzly bears in Alaska.

Director: Werner Herzog | Stars: Timothy Treadwell, Amie Huguenard, Werner Herzog, Carol Dexter

Votes: 62,267 | Gross: $3.17M

14. Cyberbully (2015 TV Movie)

62 min | Crime, Drama, Mystery

A British teenager is forced by a computer hacker to do his bidding. If she refuses, the hacker will leak compromising photos of her to the public.

Director: Ben Chanan | Stars: Maisie Williams, Ella Purnell, Wilson Haagens, Anthony Shuster

Votes: 7,921

15. Risen (2021)

109 min | Drama, Sci-Fi, Thriller

Disaster unfolds when a meteor strikes a small town, turning the environment uninhabitable and killing everything in the surrounding area.

Director: Eddie Arya | Stars: Zahlee Moore, Izzy Bridger, Lily Brown Griffiths, Dominic Stone

Votes: 3,184

16. Charlie Bartlett (2007)

R | 97 min | Comedy, Drama, Romance

A rich kid becomes the self-appointed psychiatrist to the student body of his new high school.

Director: Jon Poll | Stars: Anton Yelchin, Robert Downey Jr., Hope Davis, Kat Dennings

Votes: 67,027 | Gross: $3.95M

17. Prozac Nation (2001)

R | 95 min | Biography, Drama, Romance

A young woman struggles with depression during her first year at Harvard.

Director: Erik Skjoldbjærg | Stars: Christina Ricci, Jonathan Rhys Meyers, Jessica Lange, Anne Heche

Votes: 19,097

18. Analyze That (2002)

R | 96 min | Comedy, Crime

Mobster Paul Vitti is released into Dr. Ben Sobol's care, where only more chaos ensues.

Director: Harold Ramis | Stars: Robert De Niro, Billy Crystal, Lisa Kudrow, Joe Viterelli

Votes: 89,975 | Gross: $32.12M

19. Shopgirl (2005)

R | 106 min | Drama, Romance

A film adaptation of Steve Martin's novel about a complex love triangle between a bored salesgirl, a wealthy businessman and an aimless young man.

Director: Anand Tucker | Stars: Steve Martin, Claire Danes, Jason Schwartzman, Bridgette Wilson-Sampras

Votes: 24,813 | Gross: $10.28M

20. Little Joe (2019)

Not Rated | 105 min | Drama, Horror, Mystery

Alice, a single mother, is a dedicated senior plant breeder at a corporation engaged in developing new species. Against company policy, she takes one home as a gift for her teenage son and names it after him but soon starts fearing it.

Director: Jessica Hausner | Stars: Emily Beecham, Ben Whishaw, Kerry Fox, Kit Connor

Votes: 9,403

21. According to Greta (2009)

PG-13 | 92 min | Drama, Romance

A suicidal and rebellious teenager is sent to live with her grandparents for the summer, where life takes an unexpected turn.

Director: Nancy Bardawil | Stars: Hilary Duff, Evan Ross, Michael Murphy, Ellen Burstyn

Votes: 10,430

22. The Cry of the Owl (2009)

R | 100 min | Drama, Mystery, Thriller

A troubled young man retreats from the big city and his ex-wife for the tranquility of a small town. He is drawn into a relationship with a young woman whose boyfriend goes missing, leaving the new arrival as a suspect.

Director: Jamie Thraves | Stars: Paddy Considine, Julia Stiles, Karl Pruner, Phillip MacKenzie

Votes: 5,183

23. Hamlet 2 (2008)

R | 92 min | Comedy, Music

In this irreverent comedy, a failed actor-turned-worse-high-school-drama-teacher rallies his Tucson, AZ students as he conceives and stages politically incorrect musical sequel to Shakespeare's Hamlet.

Director: Andrew Fleming | Stars: Steve Coogan, Elisabeth Shue, Catherine Keener, J.J. Soria

Votes: 17,468 | Gross: $4.88M

24. American Dreamz (2006)

PG-13 | 107 min | Comedy, Music

A popular television music talent competition hosted by a pompous egomaniac becomes the setting for an assassination attempt when the President of the United States becomes a celebrity judge in an attempt to rehabilitate his image.

Director: Paul Weitz | Stars: Hugh Grant, Dennis Quaid, Mandy Moore, Willem Dafoe

Votes: 25,336 | Gross: $7.19M

25. Kids in the Hall: Brain Candy (1996)

R | 89 min | Comedy

A pharmaceutical scientist creates a pill that makes people remember their happiest memory, and although it's successful, it has unfortunate side effects.

Director: Kelly Makin | Stars: David Foley, Bruce McCulloch, Kevin McDonald, Mark McKinney

Votes: 9,533 | Gross: $2.65M

26. The Hedgehog (2009)

Unrated | 100 min | Drama

The life of a determined young girl is changed when she befriends her building's concierge, a solitary woman who is more than what she seems.

Director: Mona Achache | Stars: Josiane Balasko, Garance Le Guillermic, Togo Igawa, Anne Brochet

Votes: 9,814

27. Madhouse (2004)

R | 91 min | Horror, Thriller

A young psychiatric intern unearths secrets about the mental health facility in which he works.

Director: William Butler | Stars: Joshua Leonard, Jordan Ladd, Natasha Lyonne, Lance Henriksen

Votes: 6,989

28. Hannah Takes the Stairs (2007)

Not Rated | 83 min | Comedy, Drama, Romance

Hannah is a recent college graduate interning at a Chicago production company. She is crushing on two writers at work, Matt and Paul, who share an office and keep her entertained. Will a ... See full summary »

Director: Joe Swanberg | Stars: Greta Gerwig, Kent Osborne, Andrew Bujalski, Ry Russo-Young

Votes: 2,274 | Gross: $0.02M

29. Dietland (2018)

45 min | Comedy, Drama

Plum Kettle is a ghostwriter for the editor of one of New York's hottest fashion magazines.

Stars: Joy Nash, Tamara Tunie, Robin Weigert, Rowena King

Votes: 2,832

30. Off the Map (2003)

PG-13 | 105 min | Drama

An eleven-year-old girl watches her father come down with a crippling depression. Over one summer, she learns answers to several mysteries, and comes to terms with love and loss.

Director: Campbell Scott | Stars: Valentina de Angelis, Joan Allen, Sam Elliott, Amy Brenneman

Votes: 3,458 | Gross: $1.31M

31. Happiness (III) (2017)

5 min | Animation, Short, Drama

An analogy to life on Earth, Happiness tells the story of a rodent's unrelenting quest for happiness and fulfillment.

Director: Steve Cutts

Votes: 2,130

32. American Teen (2008)

PG-13 | 95 min | Documentary

A documentary on seniors at a high school in a small Indiana town and their various cliques.

Director: Nanette Burstein | Stars: Hannah Bailey, Jake Tusing, Megan Krizmanich, Colin Clemens

Votes: 4,250 | Gross: $0.94M

33. Close to Leo (2002 TV Movie)

Unrated | 88 min | Drama, Romance

When 21-year-old Leo, the oldest of four brothers, announces to his rural French family that he's HIV+ family bonds are tested. The family decides that 11-year-old Marcel, the youngest, is ... See full summary »

Director: Christophe Honoré | Stars: Yaniss Lespert, Pierre Mignard, Marie Bunel, Rodolphe Pauly

Votes: 1,128

34. Hello (II) (2008)

129 min | Drama, Romance

Call-center workers receive a phone call from God.

Director: Atul Agnihotri | Stars: Sharman Joshi, Amrita Arora, Sohail Khan, Isha Koppikar

Votes: 2,297

35. Poster Boy (2004)

R | 98 min | Drama

With the help of a hot, slightly older new acquaintence (Noseworthy), the closeted son (Newton) of a conservative U.S. Senator (Lerner) puts a shocking spin on his dad's re-election campaign.

Director: Zak Tucker | Stars: Matt Newton, Michael Lerner, Karen Allen, Jack Noseworthy

Votes: 1,437 | Gross: $0.06M

36. Hahaha (2010)

115 min | Comedy, Drama, Romance

Two friends, while having drinks together, share their memories of visiting the seaside resort of Tongyeong.

Director: Hong Sang-soo | Stars: Kim Sang-kyung, Moon So-ri, Yoo Joon-sang, Kim Gyu-ri

Votes: 1,521

37. Zombex (2013)

R | 90 min | Horror, Sci-Fi, Thriller

As things are turning around for the city, people must face a disaster of epic proportions. They are dealing with the prospect of losing the people of New Orleans as they turn into the city's walking dead.

Director: Jesse Dayton | Stars: Lew Temple, Malcolm McDowell, David Christopher, Sid Haig

Votes: 753

38. God's Club (2015)

Not Rated | 89 min | Drama

A debate about allowing school prayer pits Christians against Atheists.

Director: Jared Cohn | Stars: Stephen Baldwin, Corbin Bernsen, Lorenzo Lamas, Rico Simonini

Votes: 344

39. Magic Medicine (2018)

79 min | Documentary

In 2012 a team of medical researchers asked themselves, "what would happen if we gave psilocybin (magic mushrooms) to people suffering from severe depression"? It took them three years to get the necessary permissions to find out.

Director: Monty Wates | Stars: Robin Carhart-Harris, Rosalind Watts

Votes: 382

40. Nord (2009)

79 min | Comedy, Drama

NORTH Following a nervous breakdown, ski athlete Jomar has isolated himself in a lonely existence as the guard of a ski park. When he learns that he might be the father of a child way up ... See full summary »

Director: Rune Denstad Langlo | Stars: Anders Baasmo, Kyrre Hellum, Marte Aunemo, Mads Sjøgård Pettersen

Votes: 3,184

41. Beauty Is Embarrassing (2012)

Not Rated | 88 min | Documentary, Biography, Comedy

A documentary on the life and current times of artist Wayne White.

Director: Neil Berkeley | Stars: Wayne White, Mimi Pond, Paul Reubens, Mark Mothersbaugh

Votes: 1,218

42. Love at First Child (2015)

G | 91 min | Comedy, Romance

Ange Pagani, womanizing architect, is having a normal day until a woman, Gabrielle, arrives at his office accusing his son of being pregnant to her daughter. But Ange has no children!

Director: Anne Giafferi | Stars: Isabelle Carré, Patrick Bruel, Alice de Lencquesaing, Thomas Solivérès

Votes: 1,089

43. The Lady Terrorist (2019)

Not Rated | 95 min | Comedy, Crime, Drama

An elderly woman decides to act on her own with a rifle as she gets fed up with injustice.

Director: Radek Bajgar | Stars: Iva Janzurová, Martin Hofmann, Tatiana Dyková, Pavel Liska

Votes: 484

44. Louis Theroux: America's Medicated Kids (2010 TV Movie)

58 min | Documentary

Louis meets parents who have turned to medication to keep their children under control.

Director: Danny Horan | Star: Louis Theroux

Votes: 1,509

45. Depression Quest (2013 Video Game)

Drama

An interactive look into the daily life and choices of a person suffering from depression.

Director: Zoë Quinn

Votes: 155

46. Shrinks (I) (2007)

26 min | Short, Comedy

Five Shrinks; One Neurotic Patient; A modern comedy about mental health.

Director: Gregg Brown | Stars: Rozie Bacchi, Gregg Brown, Chella Ferrow, Robert Modica

Votes: 80

47. WSIM: What Suffered Inside Me (2008)

3 min | Animation, Short

The main character sees himself as an incomplete stick figure with a crossed line on his face. He visualizes simple figures wearing horizontal lines on their faces as unable to see his ... See full summary »

Director: Jennifer Hardy CK

48. Changing Our Minds: Clear Thoughts on Depression, Drugs and Alternative Paths to a Healthy Mind (2010 Video)

TV-PG | 92 min | Documentary

"Changing Our Minds: Clear Thoughts on Depression, Drugs and Alternative Paths to a Healthy Mind" is a new documentary film which answers the pharmaceutical industry's media blitz. Living ... See full summary »

Director: David Sousa | Stars: Mary Ann Block, Peter Breggin, Walter Brown, Marilyn Gabor

49. Almost Gone (2008)

Not Rated | 14 min | Short, Drama, Thriller

Add a Plot

Director: Jason Ramsey | Stars: Michael Catanachapodaca, Stephen Guilbert, Denise Shaw, Don Fredericksen

50. Hollywood and Vine (2008)

80 min | Drama

A night in the life of 5 dysfunctional actors, struggling to make it in Hollywood.

Director: Eric Minh Swenson | Stars: Tenaya Cleveland, Brandon Burkhart, Sarah Craveiro, David Daskal

Votes: 27