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- Cristina and Meredith's surgical skills are put to the ultimate test.
- Seattle Grace Hospital is hit with a crisis like no other in its history.
- Izzie's memory problems panic Alex, the team takes care of a John Doe who was hit by a bus, Bailey rethinks her pediatrics fellowship, and the hospital endures losses.
- The lives of everyone in the OR are threatened when a patient enters with a bomb inside him, and a young paramedic with her arm inside the cavity is the only thing keeping it from going off.
- While the man with the bomb lodged in his chest remains in Burke's OR with Meredith's hand in the cavity, Bailey's injured husband remains in Derek's. Meanwhile, Bailey's distress puts her unborn baby at risk.
- Richard is determined to discover the guilty party, and punishes the interns by making them arrange a prom for his niece. Meanwhile, Callie presses George about his feelings, and Derek and Meredith have to make a decision about Doc.
- Cristina must head to Zurich soon but she is unprepared to leave behind her life in Seattle. Fear runs amok throughout the hospital as an explosion in a shopping mall results in a mass casualty situation.
- A car crash involving students going to their college graduation takes its toll on the residents in the ER, Derek's wedding gift is uniquely suited for Meredith - even if the oversight is not. Meanwhile, Denny's return has Derek and Bailey searching for the cause, and the results will change the outcome of the day.
- Teddy is called away on another case, as Henry is brought in for surgery.
- Gandalf and Aragorn lead the World of Men against Sauron's army to draw his gaze from Frodo and Sam as they approach Mount Doom with the One Ring.
- Through the eyes of ten-year-old Alexander, we witness the delights and conflicts of the Ekdahl family, a sprawling bourgeois clan in turn-of-the-twentieth-century Sweden.
- A train wreck brings in multiple casualties, leaving Meredith hanging for her answer. Meanwhile, Alex finds working without his mojo a disheartening experience, and Cristina searches high and low for a missing appendage.
- The victims of a workplace shooting are admitted. Izzie puts her job on the line to ensure Denny gets a new heart, Callie makes an effort with Meredith, and Addison is suspicious of Derek.
- 2005– 1hTV-149.0 (1.9K)TV EpisodeBurke is admitted as a patient, along with Richard's niece. Izzie and the others fight to keep Denny alive, while Alex tries to secure the donor heart for him.
- Izzie fights to save her patient's life, George searches for the son of his patient, and Alex has to contend with the relatives of victims. Meanwhile, Meredith is unconscious underwater, with Derek her only hope.
- Meredith and Miranda each cross a line, William Dunn regrets his decision and Izzie finally confronts what Denny's appearance means.
- After a burn victim unexpectedly dies in the midst of a chaotic ER, the Chief and board member Jennings interrogate the residents to find the culprit, as all the Mercy West and Seattle Grace residents defend their actions in an effort to save their jobs.
- Teddy asks Cristina to help with an OR patient.
- A meek Hobbit from the Shire and eight companions set out on a journey to destroy the powerful One Ring and save Middle-earth from the Dark Lord Sauron.
- Owen's PTSD endangers Cristina, Izzie's illness leaves the residents dealing with guilt and anger - at her expense, and Derek's fear causes him to persevere for Meredith's answer.
- As Seattle is plunged into a major storm, Meredith goes into labour. When the hospital loses power, her doctor and all the others are forced to work in the dark. Cristina must perform surgery in almost complete darkness while Arizona, Alex, and Lauren must ward off terrified parents. Then, just outside the hospital, a school bus full of people crashes and flips over, forcing several doctors to rescue its passengers. Cristina finally confronts Owen on his desire to have kids.
- The history of the United States from the 1950s to the '70s unfolds from the perspective of an Alabama man with an IQ of 75, who yearns to be reunited with his childhood sweetheart.
- While Frodo and Sam edge closer to Mordor with the help of the shifty Gollum, the divided fellowship makes a stand against Sauron's new ally, Saruman, and his hordes of Isengard.
- An old storyteller tells European folk tales to his sarcastic dog.
- A disfigured musical genius, hidden away in the Paris Opera House, terrorizes the opera company for the unwitting benefit of a young protégée whom he trains and loves.
- The interns each react differently to a mass-casualty incident. Meanwhile, George crosses the professional line with Callie, Cristina asks Burke to keep quiet about their engagement, and Richard dons a new hairstyle.
- Sloane's facial transplant fades to the background as the interns begin squabbling, Bailey's attempts to reach Derek unexpectedly clear surgeons from the hospital, and Cristina juggles her first solo surgery with treating a resistant Izzie.
- Izzie is torn over whether to have Derek's proposed brain surgery. A soldier on medical leave asks for a radical operation so he can return to active duty. The Chief tries to lure Bailey back to general surgery with a new toy, and Mark shifts into high gear with major life changes.
- In his new role as Chief, Derek restores the hospital lecture series, and several attendings present to the group pivotal surgical cases from their pasts: Bailey reflects on how shy she was as an intern until getting advice from Webber, Callie looks back on a polio case, and Richard recalls a case in which he and Ellis worked on a patient diagnosed with AIDS, known in 1982 as GRID.
- As Meredith, Cristina, Derek, Mark, Lexie, and Arizona face the aftermath of their accident, the doctors back at the hospital face the future that seems to be taking them all in different directions.
- Meredith and Derek are at odds over whether or not to continue with their 13th clinical trial patient and the doctors lift the final critical pieces of cement from the young boy's body. Meanwhile, Alex rushes Ava into the hospital and is forced to confront the reality of her condition.
- Each of the doctors involved in the crash experiences flashbacks that take them back to their time of rescue and explain how they got to where they are now.
- The satiric adventures of a working-class family in the misfit city of Springfield.
- A drama that follows the lives of the Dillon Panthers, one of the nation's best high school football teams, and their head coach Eric Taylor.
- After the Rebel Alliance are overpowered by the Empire, Luke Skywalker begins his Jedi training with Yoda, while his friends are pursued across the galaxy by Darth Vader and bounty hunter Boba Fett.
- The wedding day arrives. Richard chooses the new Chief and Chief Resident, the interns receive their exam results, Callie drops a bombshell on George while Izzie pours her heart out to him, and Burke makes an important decision.
- When Isaac, the hospital lab tech, has an inoperable tumor wrapped around his spine, he turns to Dr. Derek Shepherd to do the impossible, and Derek tests the Chief's authority when Richard objects to moving forward with the risky surgery.
- 2005– 43mTV-148.7 (1.1K)TV EpisodeThe doctors work together to operate on two sisters joined at the head; Cristina travels to Zurich where she deals with a blast from her past; Richard voices his concern over the hospital's allegiance with the Harper Avery Foundation.
- The absurd antics of an Indiana town's public officials as they pursue sundry projects to make their city a better place.
- Filmmaker Andrew Jarecki examines the complicated life of reclusive real estate icon Robert Durst, the key suspect in a series of unsolved crimes.
- Luke Skywalker joins forces with a Jedi Knight, a cocky pilot, a Wookiee and two droids to save the galaxy from the Empire's world-destroying battle station, while also attempting to rescue Princess Leia from the mysterious Darth Vader.
- 1971– 1h 31mTV-G8.6 (187)TV Episode
- Meredith is horrified when her mother is admitted, and everyone is concerned when Cristina collapses in the operating room. Meanwhile, Addison is determined to save a very sick baby.
- George finally gets laid but gets syphilis. It's rampant among staff. Surgeon Webber is losing his sight. He wants Shepherd to operate secretly. A male patient has an ovary. A lifesaving autopsy's performed without consent.
- A traumatic car accident fills the ER. Cristina has a crisis of conscience about her deceptive teamwork with Burke, Izzie pushes the boundaries of her probation, and Callie tries to explain herself to George.
- George's father's surgery has left him very weak, Izzie's act of generosity backfires on her, Cristina and Burke continue their war of silence, and Meredith reaches out to her father.
- A surgical team battles the clock as they try to save a boy encased in cement, Karev's situation with an ever-disintegrating Ava brings back painful memories that interfere with his judgment, Derek and Meredith have one last chance at their clinical trial.
- Derek's mother visits, the death row patient starts angling for death in the hospital, Izzie craves more in her relationships, and Jackson's need for organs becomes critical.
- Derek's malpractice deposition reveals an unhappy statistic, the interns finally diagnose 'Patient X', Karev stands up to two attendings to save a band geek, and when Webber shuts Miranda out completely she makes a call.
- Addison and Derek differ on the treatment plan for their patient, Cristina discovers malpractice in high places, Izzie gets bad news, and Mark spectacularly mistimes his confession.