With E4 (Sorted by Popularity Ascending)
2. The Sopranos (1999–2007)
TV-MA | 55 min | Crime, Drama
New Jersey mob boss Tony Soprano deals with personal and professional issues in his home and business life that affect his mental state, leading him to seek professional psychiatric counseling.
3. Supernatural (2005–2020)
TV-14 | 44 min | Drama, Fantasy, Horror
Two brothers follow their father's footsteps as hunters, fighting evil supernatural beings of many kinds, including monsters, demons and gods that roam the earth.
4. The Big Bang Theory (2007–2019)
TV-PG | 22 min | Comedy, Romance
A woman who moves into an apartment across the hall from two brilliant but socially awkward physicists shows them how little they know about life outside of the laboratory.
7. The 100 (2014–2020)
TV-14 | 43 min | Drama, Mystery, Sci-Fi
Set ninety-seven years after a nuclear war has destroyed civilization, when a spaceship housing humanity's lone survivors sends one hundred juvenile delinquents back to Earth, in hopes of possibly re-populating the planet.
12. Young Sheldon (2017– )
TV-PG | 30 min | Comedy
Meet a child genius named Sheldon Cooper; (already seen as an adult in The Big Bang Theory (2007)) and his family. Some unique challenges face Sheldon who seems socially impaired.
14. Back to the Future (1985)
PG | 116 min | Adventure, Comedy, Sci-Fi
Marty McFly, a 17-year-old high school student, is accidentally sent thirty years into the past in a time-traveling DeLorean invented by his close friend, the eccentric scientist Doc Brown.
Votes: 1,086,198 | Gross: $210.61M
16. The O.C. (2003–2007)
TV-PG | 44 min | Comedy, Drama, Romance
A troubled youth becomes embroiled in the lives of a close-knit group of people in the wealthy, upper-class neighborhood of Newport Beach, Orange County, California.
21. Smallville (2001–2011)
TV-PG | 60 min | Adventure, Drama, Romance
A young Clark Kent struggles to find his place in the world as he learns to harness his alien powers for good and deals with the typical troubles of teenage life in Smallville, Kansas.
24. One Tree Hill (2003–2012)
TV-14 | 60 min | Drama, Romance, Sport
Half-brothers Lucas and Nathan Scott trade between kinship and rivalry both on the basketball court and in the hearts of their friends in the small, but not so quiet town of Tree Hill, North Carolina.
28. Die Hard (1988)
R | 132 min | Action, Thriller
An NYPD officer tries to save his wife and several others taken hostage by German terrorists during a Christmas party at the Nakatomi Plaza in Los Angeles.
Votes: 806,427 | Gross: $83.01M
29. Skins (2007–2013)
TV-MA | 46 min | Drama
The story of a group of British teens who are trying to grow up and find love and happiness despite questionable parenting and teachers who more want to be friends (and lovers) rather than authority figures.
32. Happy Endings (2011–2020)
TV-14 | 22 min | Comedy, Romance
This Chicago-set sitcom follows the intertwined lives of six young urbanites trying to learn the ropes of adulthood. Through breakups and whatever other curve-balls life throws them, the pals stick together.
38. Home Alone (1990)
PG | 103 min | Comedy, Family
An eight-year-old troublemaker must protect his house from a pair of burglars when he is accidentally left home alone by his family during Christmas vacation.
Votes: 498,070 | Gross: $285.76M
42. Ghost Whisperer (2005–2010)
TV-PG | 60 min | Drama, Fantasy
A newlywed with the ability to communicate with the earthbound spirits of the recently deceased overcomes skepticism and doubt to help send their important messages to the living and allow the dead to pass on to the other side.
44. Limitless (I) (2011)
PG-13 | 105 min | Sci-Fi, Thriller
With the help of a mysterious pill that enables the user to access 100% of his brain's abilities, a struggling writer becomes a financial wizard, but it also puts him in a new world with many dangers.
Votes: 535,390 | Gross: $79.25M
49. Naked Attraction (2016– )
60 min | Game-Show, Romance
A controversial dating series in which people see potential love interests whose naked bodies are gradually revealed to them. Then they must get naked themselves and choose.
50. Back to the Future Part III (1990)
PG | 118 min | Adventure, Comedy, Sci-Fi
Stranded in 1955, Marty McFly learns about the death of Doc Brown in 1885 and must travel back in time to save him. With no fuel readily available for the DeLorean, the two must figure how to escape the Old West before Emmett is murdered.
Votes: 413,747 | Gross: $87.73M