Quinn, Rembrandt and Maggie find Quinn's long-lost younger brother Colin on a world with mid 19th Century morals and technology. On the next world, the doubles of Colin's love interest Susanna and her mother recruit him to commit a crime.
The Sliders arrive on a world where World War II never took place and fascists rule California and are making headway into the rest of the United States. Rembrandt is abducted.
In a world where tattooed humans are hunted for sport by the new Kromaggs/Human half-breeds, the Sliders attempt to save a captive Colin. Rembrandt is poisoned and needs the help of his enemy to survive.