A policeman white blood cell, with the help of a cold pill, must stop a deadly virus from destroying the human they live in, Frank.A policeman white blood cell, with the help of a cold pill, must stop a deadly virus from destroying the human they live in, Frank.A policeman white blood cell, with the help of a cold pill, must stop a deadly virus from destroying the human they live in, Frank.
- Directors
- Writer
- Stars
- Laurence Fishburne(voice)
- Chris Rock(voice)
- David Hyde Pierce(voice)
Top credits
- Directors
- Writer
- Stars
- Laurence Fishburne(voice)
- Chris Rock(voice)
- David Hyde Pierce(voice)
- Awards
- 1 win & 8 nominations
Videos1
David Hyde Pierce
- Drixas Drix
- (voice)
Brandy Norwood
- Leahas Leah
- (voice)
- Directors
- Writer
- Production, box office & more at IMDbPro
- All cast & crew
Storyline
Frank Detorre is a slovenly zoo keeper, and simple father to the only young and bright girl named Shane, who catches a cold right after he swallowed a germ-ridden egg! The inside of his body is known as the "City of Frank". An unlikely hero of a policeman white blood cell, by the name of Osmosis Jones, works as a member of Immunity cell. But with that germ-ridden egg comes a mortal danger: Osmosis discovers Frank has really contracted a villainous and black-hearted deadly virus known as Thrax who arrives and is plotting to ultimately overheat Frank's body, killing him from the inside out! Thrax is motivated by trying to become the nastiest new virus, attempting to kill each new victim faster than the previous. His grandiose plan for Frank is death in 48 hours, breaking previous medical records! Meanwhile the pill that Frank took, Drix arrives in the body and covers Frank's throat with ice to cover the irritation. Osmosis Jones becomes his newest partner. Now it's all up to only Osmosis and Drix to put an end of Thrax's plans before Frank gets sick forever and Shane will become an orphan! —Anthony Pereyra <hypersonic91@yahoo.com>
- Taglines
- An epic adventure of microscopic proportions.
- Genres
- Motion Picture Rating (MPAA)
- Rated PG for bodily humor
- Parents guide
Did you know
- TriviaAt 01:01:04 into the movie, Osmosis Jones walks into the Chief's office and says "Brandy! I mean, Leah. Why are you here?" He is speaking to the mayor's aide Leah, who is voiced by Brandy Norwood. Chris Rock unintentionally ad-libbed that line and the filmmakers decided to put it in.
- GoofsWhen Osmosis comes back from "The Zit" he greets Leah by saying "Brandy- oh I mean Leah". Brandy Norwood was the voice of Leah. The error was left in because it was acted so well and was funny.
- Crazy creditsThe title appears as bubbles, which then pop after 5 seconds.
- Alternate versionsOn some streaming services, the score plays on the soundtrack as opposed to a pop song during the opening scene.
- ConnectionsEdited into Ozzy & Drix: Home with Hector (2002)
- SoundtracksTurn It Out
Written by Kelvin Mercer, Trugoy The Dove (as David Jolicoeur) and Richard Morninglane
Produced by R. Thentic and De La Soul
Performed by De La Soul featuring Yummy Bingham (as Elizabeth "Yummy" Bingham)
De La Soul appears courtesy of Tommy Boy Music
Top review
Very inventive!
Okay, I think I've found the Sadly Underrated Movie of the Year.
I think that, between this and "the Iron Giant", Warner Brothers Animation has GOT to spring for a better promotion department. Really, all they'd have to say is something like: "We just let the creators of 'Something About Mary' and 'Dumb and Dumber' make their own cartoon. Brace yourselves."
All complaints aside, and none of them are really the movie's fault, this is one of the most inventive animated films I've seen in a very long time. The characters and backgrounds are allowed to look and move in ways that are downright refreshingly bizarre. The visuals are very imaginative. The humor, while funny, is still very much what you'd expect from a Farelly Brothers movie that takes place inside a very sick man, so I wouldn't recommend it to little kids or the weak of stomach. If you have a little future A+P major, however, this is going to blow their mind. Give it a look!
I think that, between this and "the Iron Giant", Warner Brothers Animation has GOT to spring for a better promotion department. Really, all they'd have to say is something like: "We just let the creators of 'Something About Mary' and 'Dumb and Dumber' make their own cartoon. Brace yourselves."
All complaints aside, and none of them are really the movie's fault, this is one of the most inventive animated films I've seen in a very long time. The characters and backgrounds are allowed to look and move in ways that are downright refreshingly bizarre. The visuals are very imaginative. The humor, while funny, is still very much what you'd expect from a Farelly Brothers movie that takes place inside a very sick man, so I wouldn't recommend it to little kids or the weak of stomach. If you have a little future A+P major, however, this is going to blow their mind. Give it a look!
helpful•479
- La Gremlin
- Dec 4, 2001
Details
- Release date
- Country of origin
- Official site
- Language
- Also known as
- Осмозіс Джонс
- Filming locations
- Production companies
- See more company credits at IMDbPro
Box office
- Budget
- $70,000,000 (estimated)
- Gross US & Canada
- $13,596,911
- Opening weekend US & Canada
- $5,271,248
- Aug 12, 2001
- Gross worldwide
- $14,026,418
- Runtime1 hour 35 minutes
- Sound mix
- Aspect ratio
- 2.39 : 1
Contribute to this page
Suggest an edit or add missing content

Recently viewed
Please enable browser cookies to use this feature. Learn more.