In an uncharted island in the Western Pacific, the scientist Dr. Preston King is researching the use of stem cells entwined with shark cells with Dr. Krause and the exiled Dra. Katie Medevenko to heal cancer. Out of the blue, Dr. King invites his former boss and colleagues from a pharmaceutic company where he worked to see his progress. The greedy owner of the company, Whitney Feder, goes with his "bimbo" Julie; the biologist Amelia Lockhart and her boyfriend, the IT manager Tom Reed; and the assistants Amos Bernie and Jane Harper. Dr. King welcomes the guests on the arrival and soon Tom learns that Amelia was the fiancee of Dr. King's son, Paul, who died of cancer. After dinner, Dr. King presents his research, and the group learns that Paul is alive, half-man and half-shark. Further, Dr. King is a mad scientist that is seeking revenge against Feder and his company, and Paul is hunting them down.
—Claudio Carvalho, Rio de Janeiro, Brazil