The deliveryman (Cleto Augusto) who drops off Martin Crane's easy chair in the first episode is the same deliveryman who takes it away in the final episode. Aside from the regular cast, he is also the only person to appear in both episodes.
In the pilot episode, Frasier and Martin have a fight over Frasier just wanting to hear "thank you" from Martin for allowing him to move in. Before John Mahoney (Martin) hugs Kelsey Grammer goodbye in the finale, his line is "Thank you, Frasier."
When Frasier is wrapping up his final radio broadcast, staff of the show such as Bob Dailey (co-executive producer), Jeffrey Richman (executive producer), Joe Keenan (executive producer), Maggie Blanc (producer) and Peter Casey (creator) can be seen behind the soundproof glass.
The poem Frasier is quoting at the end of the episode is "Ulysses", written by Alfred Lord Tennyson.
It won an Emmy Award for Outstanding Multi-Camera Picture Editing for a Series.