The hospital finds itself invaded by a group of anti-vivisectionists and the object of a well-orchestrated letter writing campaign against the hospital's research practices. Mr. Holland is worried about how the charitable institution will continue should donations decline substantially. The hospital treats a woman who appears to be poor and attempted suicide. The suicide attempt was real but the woman it turns out is a well-known stage entertainer, Grace Barnes. Dr. Head gladly treats her as he has his own theories about mental incapacity and its effect on physical ailments. He also decides to experiment on himself. Nurse Nellie Bowers, a probationer who feels somewhat out of place at the London, has a secret that may force her to leave the hospital and the nursing profession altogether.