The destruction of the ER that resulted in the grand opening scene here took place in I Am the Apocalypse (2015).
Dr. Charles and Jamie talk about the Fast and the Furious film series which Dr. Charles says he's never seen. Brian Tee, who plays Dr. Ethan Choi, was D.K. in the third installment of the film series, The Fast and the Furious: Tokyo Drift.
All the episodes in this first season have one-word titles.