Vanessa relives the memories of her ancestor, Lily Van Helsing, in Colonial Hong Kong. There, she learns to control her dark side and fights the B'ah, the second vampire Elder.
Sam tries to make Mohamad in to a worthy partner after he realizes his dark destiny. Scab and Ivory become daywalkers and return home to find the Sisterhood destroyed.
Vanessa, Scarlett and Axel battle the Second Elder's forces in San Francisco. Flesh, Doc, Julius and Jolene rejoin what is left of American civilization in Denver.
Sam approaches his destiny. Mohamad tries to escape his servitude and imprisonment. Axel leads the San Francisco refugees to Denver. Ivory and Scab assume control of the Daywalker horde.