There is a scene when Doctor Brock Holt (John Stamos) says to Chanel (Emma Roberts), "A, you're going to Blood Island alone, because I'm still creeped out about those STDs, and two, aren't you a little upset that your friend just got murdered?" He also says "A, and two" frequently in Full House.
The music playing when Chanel (Emma Roberts) and Munsch (Jamie Lee Curtis) are running down the hallway is the same music that used to play when Sue Sylvester ran down the hallways in Ryan Murphy's show, Glee (2009).
Emma Roberts (Chanel Oberlin) and Taylor Lautner (Dr. Cassidy Cascade) previously starred in the movie Valentine's Day (2010) together.
Abigail Breslin (Chanel #5) and Lea Michele (Hester) previously starred together in the movie 'New Year's Eve (2011)