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1-12 of 12
- In 1990s Pittsburgh, a medicine peddler starts a relationship with a young woman suffering from Parkinson's disease.
- The youngest son of an alcoholic former boxer returns home, where he's trained by his father for competition in a mixed martial arts tournament - a path that puts the fighter on a collision course with his estranged, older brother.
- The relationship of a contemporary married couple, charting their evolution over a span of years by cross-cutting between time periods.
- A homicide investigator digs deeper into a case involving a trained military sniper responsible for a mass shooting.
- Hazel and Gus are teenagers who meet at a cancer support group and fall in love. They both share the same acerbic wit and a love of books, especially "An Imperial Affliction", so they embark on a journey to visit an author in Amsterdam.
- A married couple's life is turned upside down when the wife is accused of a murder.
- A young man sets out to uncover the truth about his life after finding his baby photo on a missing persons website.
- A salesman for a natural gas company experiences life-changing events after arriving in a small town, where his corporation wants to tap into the available resources.
- New Year's Eve 1975: Two cop detectives are staking out Renzo. He's suspected of killing a cop among others. Will the 2 cops do the necessary to get their man?
- A murdered boys spirit seeks revenge by seeking six souls to live again.
- Spider, a young gang leader, gets in over his head when he robs a notorious gangster. On the run, he's taken in by a sheltered young woman and her reclusive uncle, a legendary mobster gunned down by the same gangster now pursuing Spider.
- At the Three Rivers Hospital in Pittsburgh, a clinic specializing in organ transplants, Dr. Andy Yablonski is the highly-skilled workaholic lead organ transplant surgeon, whose good-natured personality and sarcastic wit makes him popular with both his patients and colleagues. His co-workers include Dr. Miranda Foster, a surgical specialist with a rebellious streak and fiery temper who strives to live up to her deceased father's excellent surgical reputation; Dr. David Lee, a womanizing surgical resident who's broken as many hearts as he's replaced; Ryan Abbott, the inexperienced new transplant coordinator who arranges the intricately choreographed process of quickly and carefully transporting organs from donor to patient; Dr. Sophia Jordon, the dedicated head of surgery who has no patience for anyone who hasn't sacrificed as much as she has for the job; and Pam Acosta, Andy's no-nonsense operating assistant and best friend. In the season opener, a young pregnant woman's life hangs in the balance when she suffers a massive heart attack and Andy tells her that the only way to save her is for her to undergo a heart transplant. When complications arise with the donor's family, whom is a fatally injured construction foreman, Andy races the clock to save not only her life but that of her unborn child.