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- A group of doctors at Chastain Memorial Hospital face personal and professional challenges on a daily basis.
- After a bad break-up, Jess, an offbeat young woman, moves into an apartment loft with three single men. Although they find her behavior very unusual, the men support her - most of the time.
- A young woman tries to cope with life while coming to terms with her abilities as a psychic. She can see everyone's futures, but her present is a mess.
- Meet the people flying between LA and Vegas on weekends.
- The Story of César Chávez, Dolores Huerta, and a Great Movement for Social Justice.
- A team of renowned paranormal investigators set out to document supernatural and paranormal activity within the Latino and urban communities, allowing subjects to participate in their own investigation. Through personal interviews and a real-life thought-provoking approach, "From Beyond" investigates the cultural, historical and psychological aspects behind the haunting stories that the families and locations have to tell.
- A depression era outlaw, lost in the desert, seeks answers about his future from a dark enchantress - but it's his past he should be worried about.
- The doctors of Chastain are surrounded by new rules and doctors, as Red Rock Mountain Medical takes over the hospital; Conrad finds himself in a dangerous situation when the construction for a neurosurgery center causes a gas explosion.
- In an effort to save Chastain, Bell considers selling the hospital to a conglomerate, but Kit tries to make him see that the negatives will outweigh the positives. With Conrad's help, Nic tracks down Kyle and pleads for him to reconsider donating a kidney to Jessie. Meanwhile, Mina voices her concern to Austin when Shira is assigned to Micah's surgery and Devon fights for the care of a patient whom the doctors suspect is uninsured.
- When a police officer brings in an injured criminal, the staff must keep him alive; Nic gets roped into a surgical rotation with Cain that leaves her questioning the way he operates; Conrad makes a shocking discovery about the hospital.
- Intending to garner publicity for the hospital, Cain tries to recruit Bell and Kit on a dangerous surgery; the Raptor develops an emotional attachment to a patient; Mina's friend arrives with shocking news.
- After a plane crashes in Atlanta, Devon is overcome by guilt at the thought that he could have prevented the tragedy. Bell, who was a passenger on the plane, makes it his personal mission to save the life of the man seated next to him. Meanwhile, Adaku returns to ask Mina a big favor, the Raptor struggles with telling his adoptive parents about meeting his biological father and Conrad and Nic consider risking it all to investigate a drug that might be linked to Jessie's death.
- Conrad doubts Devon's judgement when a patient who was pronounced dead suddenly revives; Cain and Nic butt heads over the care of a white supremacist; The Raptor and Mina uncover new information about Red Rock Medical.
- On National Nurses' Day, Chastain's nurses are severely understaffed and overworked, leaving them all feeling exhausted and underappreciated. Cain performs a dangerous surgery on a new patient he won in a game of poker. Meanwhile, Conrad discovers that his father has been administered the same drug that he fears played a role in Jessie's death, The Raptor comes face-to-face with his birth mother for the first time and Irving attempts to take the next step in his relationship with Jessica.
- When one of Chastain's own is brought into the emergency room with life-threatening injuries, the staff rallies around each other to try to save her life, while disagreements over how to best handle her care put Cain at odds with the rest of the doctors. Also, Bell is met with an unexpected response when he voices concerns regarding the nursing shortage that Nic brought to his attention. Meanwhile, Conrad turns heads when he shares data about Hemopleatin, and Kyle begins volunteering at the hospital.
- Upon dubbing Thanksgiving "the most dangerous day of the year," Devon and Irving are inundated with patients in the ER. When an A-list celebrity enters the hospital after swallowing a wish bone, Logan Kim assigns a new surgeon to the case in the hopes of garnering extra publicity. Meanwhile, tensions run high at the Raptor home when he hosts his biological and adoptive families for a Thanksgiving dinner and Kyle interrupts Nic and Conrad's low-key plans.
- On Devon's last day as an intern, he and Conrad are faced with a moral dilemma over a suicidal patient who is in need of a liver transplant. When Bell discovers that Cain is keeping braindead patients alive in order to boost his survival rates and add to Red Rock's profits, he decides to take matters into his own hands. Meanwhile, Adaku goes into early labor, causing a strain on her heart and Mina is left in doubt over how to best handle her care.
- After being terminated from Chastain, Conrad has difficulty figuring out his next step and distracts himself by accompanying a patient on a zero-gravity adventure. In his first move as the new Chief of Surgery, Cain puts the doctors on a commission-based pay system, which causes Devon's new intern to agree to a procedure before weighing the risks. Meanwhile, Mina struggles with taking care of Adaku's baby and Bell's supplement company gets its big break.
- While working at their non-profit clinic three hours outside of Atlanta, Nic and Mina treat a patient with a failing heart VAD, forcing them to find a new battery in time to save her life. Conrad gets a call from a previous patient in crisis after being sued by Red Rock for medical expenses he can't afford. Meanwhile, Devon's VIP patient, Nadine, returns to the ER and Cain tries to get close to Bell's business partner from the supplement company.
- Upon meeting with a high-profile soccer player suffering from mysterious symptoms, Conrad ends up back at Chastain and faces an angry Logan Kim. When Bell and the Raptor come up empty-handed in regard to a diagnosis, the doctors take note on how talented Conrad truly is. Nic springs into action when she notices Kyle falling into a deep depression and fears he could be suicidal.
- Cain feels disrespected by Logan Kim when he is left out of a major decision regarding Conrad. Meanwhile, the doctors work together to try to save the lives of two big Red Rock donors who were involved in a jet skiing accident. Then, Irving and Devon realize that three of their patients, all with different symptoms, could actually be triggered by the same thing. Also, Bell's supplement company proves to be more lucrative than anyone anticipated, but an unexpected snag could put it in jeopardy.
- The new neurosurgery center opens, and Nic is forced to work alongside Cain again; a heart transplant has an unexpected result; Bell asks Conrad to reexamine three patients who may have been poisoned.
- When Nadine's father comes to town for her birthday, Devon enlists the help of the whole staff, as well as one of his patients, to ensure that he makes the best first impression. Red Rock decides to cut the entire OBGYN department and Logan Kim leaves Conrad with the difficult task of letting the residents go. Meanwhile, Nic cares for a teenage patient whose condition is deteriorating.
- A renowned pediatric surgeon is called over to Chastain for an extremely difficult surgery on a newborn, but when she arrives, The Raptor and Devon realize she is not fit for surgery, resulting in a situation more complicated than they could have imagined. Meanwhile, a Dolly Parton drag queen is admitted to the ER after collapsing on stage, leading Bell and Ezra to a potentially life-saving discovery. Also, Nic and Conrad suspect their patient may be the victim of sex trafficking and Nadine delivers some surprising news to Devon.
- Conrad finds himself caught between his duties as a doctor and his loyalty to Kitt, when he discovers that her son-in-law may be suffering from a serious disease. While moonlighting at a long-term care facility, Devon and Nic make a shocking discovery about a former patient who fell victim to Cain's manipulative practices. Meanwhile, after jumping into a new opportunity as a TV doctor, Bell is left without any surgeries and The Raptor brings him in to help on an important case.