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- Chronicles the lives of a group of midwives living in East London in the late 1950s to late 1960s.
- The everyday lives of working-class inhabitants of Albert Square, a traditional Victorian square of terrace houses surrounding a park in the East End of London's Walford borough. The square includes the Queen Vic pub and a street market.
- The daily lives of staff at a Birmingham medical practice, including their often-dramatic involvements with their patients.
- The everyday lives of the people frequenting the frenetic Accident and Emergency department of Holby City Hospital.
- The everyday lives, professional and personal, of the doctors, nurses and patients who find themselves, for various reasons, in the wards of the frenetic cardiac unit of Holby City General Hospital.
- Set in the mid-90s at the height of Cool Britannia, a drama based on real diaries takes an honest look at teenage life through the eyes of funny, music-mad Rae
- Crippled by his writer's block, Paul enters into a new, exciting relationship with risk-taking Billy and super-sexy Juliette. As it becomes increasingly tangled, however, he must choose one of them over the other.
- Customs officer Marcus Ashton joins a new team hunting Britain's most wanted criminals, based on Cameron Addicott's book.
- Two best friends, one who has nothing going for him and the other with top grades and a bright future want to take their grime to the next level. When Yems (Ade Oyefeso) meets a girl at College he gains an immediate attraction for her, they become good friends and all three of them form a group called the "Youngers".
- The second in Penny Woolcock's Tina trilogy, Tina Takes A Break was made in 2001 and is the best of the TV outings. Set on a tough housing estate in Beeston, Leeds and employing the real folk who live their to play the characters, the first film had a Shameless like exuberance that depicted the residents as akin to rough diamonds, doing what they had to to survive. This second film is the other side of the coin, opting for poignancy as the rough and ready lifestyle of the estate is shown through the eyes of infants.
- Set in Bradford's City Park, this stunning live performance combines the vibrancy of Bollywood with Bizet's classic opera Carmen.
- If life is about change, a bored, single and seemingly friendless office worker needs a big one. But will a big material change alter the fabric of who he is or what he sees in the world? Does living always mean changing?
- Terry is Biz's best friend, or should that be was? Terry needs to steady his emotions, and soon. Over the course of an afternoon, he analyses their time together, remembering the reasons why they were friends in the first place.
- Dot makes a hard decision while Jim is forced to see the error of his ways, Phil is shocked when Ben makes a shocking confession and Little Mo realises she has to put the past behind her.
- Gina Hope tells Connie that she wishes to go to an assisted suicide clinic in Switzerland and enlists her help in filing the application. Connie at first refuses but after hearing a taped message than Gina made for Elliott she agrees. Matt continues to question the validity of the drugs available in Holby and enlists Reg's help. They run tests on samples from the Holby pharmacy and find that the drugs are below par in nearly all cases and nearly results in Ric losing an obese man on the operating table.
- A victim turns vigilante when a drug lord runs down an old woman; Harry doesn't want a fuss made on his last day but his staff are not easily dissuaded; paramedic Jeff starts and irritates gay boss Dixie by trying to call her feminine pet names; Harry and Selina kiss in full for the first time - witnessed by boo hiss villain Nathan.
- Dot is determined to keep Tomas safe while Jim searches for his mother.
- With Gem's help, Rash makes the choice to follow his dream of traveling. Will risks Connie's wrath to help a patient.
- A terrorist attack on a market leaves Ethan with a difficult choice and leads to Rash returning to the ED immediately after his mother's funeral.
- David and Ollie continue to butt heads. Rash decides to fight to stay at Holby. A new member joins the paramedic team.
- Part One. New colleague, Toby de Silva, is immediately thrown into the deep end when he joins Holby City's A&E Department when a bomb goes off on a Coach, and is unfortunate enough to experience what is possibly the worst first day any employee has ever had to endure.
- Events occur in parallel with the previous episode but from alternative perspectives. Animal rights activists end up in Casualty when their bombing campaign backfires. New doctor Toby starts and is quickly nicknamed Dracula - "because he sucks"