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- CreatorChuck LorreBill PradyStarsJohnny GaleckiJim ParsonsKaley CuocoAspiring film actress Penny moves into a Pasadena apartment across the hall from brilliant, but socially awkward, physicists Sheldon Cooper and Leonard Hofstadter and shows them how little they know about life outside of the lab.
- CreatorCarter BaysCraig ThomasStarsJosh RadnorJason SegelCobie SmuldersA father recounts to his children - through a series of flashbacks - the journey he and his four best friends took leading up to him meeting their mother.
- CreatorLee AronsohnChuck LorreStarsJon CryerAshton KutcherAngus T. JonesA hedonistic jingle writer's free-wheeling life comes to an abrupt halt when his brother and 10-year-old nephew move into his beach-front house.
- StarsTiff NeedellJeremy ClarksonQuentin WillsonQuentin, Tiff, Vicki and others look at all things car-related.
- CreatorBill LawrenceStarsZach BraffDonald FaisonSarah ChalkeIn the unreal world of Sacred Heart Hospital, intern John "J.D." Dorian learns the ways of medicine, friendship and life.
- CreatorLarry DavidJerry SeinfeldStarsJerry SeinfeldJulia Louis-DreyfusMichael RichardsThe continuing misadventures of neurotic New York City stand-up comedian Jerry Seinfeld and his equally neurotic New York City friends.
- CreatorBruce HelfordStarsCharlie SheenShawnee SmithNoureen DeWulfEx-baseball-player Charlie is an anger-management therapist who has small-group sessions at home, an OCD teen daughter, an ex-wife, and a sex-buddy/therapist.
- CreatorDavid ChaseStarsJames GandolfiniLorraine BraccoEdie FalcoNew Jersey mob boss Tony Soprano deals with personal and professional issues in his home and business life that affect his mental state, leading him to seek professional psychiatric counseling.
- CreatorTom FontanaStarsErnie HudsonJ.K. SimmonsLee TergesenA series chronicling the daily activities of an unusual prison facility and its criminal inhabitants.
- CreatorFrank DarabontStarsAndrew LincolnNorman ReedusMelissa McBrideSheriff Deputy Rick Grimes wakes up from a coma to learn the world is in ruins and must lead a group of survivors to stay alive.