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- CreatorDavid CraneMarta KauffmanStarsJennifer AnistonCourteney CoxLisa KudrowFollows the personal and professional lives of six twenty to thirty year-old friends living in the Manhattan borough of New York City.
- CreatorCarter BaysCraig ThomasStarsJosh RadnorJason SegelCobie SmuldersA father recounts to his children - through a series of flashbacks - the journey he and his four best friends took leading up to him meeting their mother.
- CreatorLee AronsohnChuck LorreStarsJon CryerAshton KutcherAngus T. JonesA hedonistic jingle writer's free-wheeling life comes to an abrupt halt when his brother and 10-year-old nephew move into his beach-front house.
- CreatorBill LawrenceStarsZach BraffDonald FaisonSarah ChalkeIn the unreal world of Sacred Heart Hospital, intern John "J.D." Dorian learns the ways of medicine, friendship and life.
- CreatorSteven LevitanChristopher LloydStarsEd O'NeillSofía VergaraJulie BowenThree different, but related, families face trials and tribulations in their own uniquely comedic ways.
- CreatorSeth MacFarlaneDavid ZuckermanStarsSeth MacFarlaneAlex BorsteinSeth GreenIn a wacky Rhode Island town, a dysfunctional family strives to cope with everyday life as they are thrown from one crazy scenario to another.
- CreatorJames L. BrooksMatt GroeningSam SimonStarsDan CastellanetaNancy CartwrightHarry ShearerThe satiric half-hour adventures of a working-class family in the misfit city of Springfield.
- CreatorVince GilliganStarsBryan CranstonAaron PaulAnna GunnA chemistry teacher diagnosed with inoperable lung cancer turns to manufacturing and selling methamphetamine with a former student in order to secure his family's future.
- CreatorVince GilliganPeter GouldStarsBob OdenkirkRhea SeehornJonathan BanksThe trials and tribulations of criminal lawyer Jimmy McGill in the years leading up to his fateful run-in with Walter White and Jesse Pinkman.
- CreatorCarlo BernardChris BrancatoDoug MiroStarsPedro PascalWagner MouraBoyd HolbrookA chronicled look at the criminal exploits of Colombian drug lord Pablo Escobar, as well as the many other drug kingpins who plagued the country through the years.
- CreatorBruce HelfordStarsCharlie SheenShawnee SmithNoureen DeWulfEx-baseball-player Charlie is an anger-management therapist who has small-group sessions at home, an OCD teen daughter, an ex-wife, and a sex-buddy/therapist.
- CreatorShana Goldberg-MeehanScott SilveriStarsMatt LeBlancPaulo CostanzoDrea de MatteoIn this spin-off of Friends (1994), Joey Tribbiani moves to Los Angeles to pursue his acting career.
- CreatorDavid CraneJeffrey KlarikStarsMatt LeBlancStephen ManganTamsin GreigA couple of British TV producers move to Hollywood to export their most popular series, and find it is not what they expected.
- CreatorScott SilveriStarsMatthew PerryLaura BenantiJulie WhitePressured by his boss to join a support group because he can't move forward after his wife's death, an irreverent sportscaster finds connection with the extremely varied members.
- CreatorAlex BarnowMarc FirekMatthew PerryStarsMatthew PerryAndrea AndersJames LesureBen Donovan manages The Sunshine Centre, a second-rate sports arena in San Diego.
- CreatorChuck LorreBill PradyStarsJohnny GaleckiJim ParsonsKaley CuocoAspiring film actress Penny moves into a Pasadena apartment across the hall from brilliant, but socially awkward, physicists Sheldon Cooper and Leonard Hofstadter and shows them how little they know about life outside of the lab.
- CreatorGreg DanielsRicky GervaisStephen MerchantStarsSteve CarellJenna FischerJohn KrasinskiA mockumentary on a group of typical office workers, where the workday consists of ego clashes, inappropriate behavior, tedium and romance.
- CreatorJennifer FlackettAndrew GoldbergNick KrollStarsNick KrollJohn MulaneyJessi KleinTeenage friends find their lives upended by the wonders and horrors of puberty.
- CreatorMike FlanaganStarsMichiel HuismanCarla GuginoHenry ThomasFlashing between past and present, a fractured family confronts haunting memories of their old home and the terrifying events that drove them from it.
- CreatorDJ NashStarsJ.K. SimmonsEli BakerAva Deluca-VerleyA typical family in the middle of a divorce: two kids, mom, dad, and guide dog. Oh, and dad's blind.
- CreatorRobert L. BoyettRobert HornStarsKelsey GrammerMartin LawrenceRory O'MalleyTwo lawyers from different backgrounds form an unlikely partnership after meeting in court during personal crises, finding balance between ethics and pragmatism.
- CreatorRon LeavittMichael G. MoyeStarsEd O'NeillChristina ApplegateKatey SagalAl is the quintessential working class dad. Peggy, his wife, always wants more from him. With their children, they go through the highs and lows of ordinary life.
- CreatorDamon JonesMichaela WatkinsStarsEliza CoupeJay HarringtonCarter MacIntyreA corporate lawyer who loses her career, her status, and her fiance takes a job at the only place that will hire her: the Public Defender's office.
- CreatorTom HertzStarsPatrick WarburtonMegyn PriceOliver HudsonTwo couples and their single friend, all at different stages in their relationships, deal with the complications of dating, commitment, and marriage.
- CreatorAziz AnsariAlan YangStarsAziz AnsariEric WareheimLena WaitheThe personal and professional life of Dev, a 30-year-old actor in New York.