The quirky spin on Conan Doyle's iconic sleuth pitches him as a "high-functioning sociopath" in modern-day London. Assisting him in his investigations: Afghanistan War vet John Watson, who's introduced to Holmes by a mutual acquaintance.
Detective Sherlock Holmes and his stalwart partner Watson engage in a battle of wits and brawn with a nemesis whose plot is a threat to all of England.
An aged, retired Sherlock Holmes deals with dementia, as he tries to remember his final case, and a mysterious woman, whose memory haunts him. He also befriends a fan, the young son of his housekeeper, who wants him to work again.