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- CreatorSusanna FogelMarco LagardeJoni LefkowitzStarsItalia RicciMary Page KellerRichard BrancatisanoApril Carver, whose world has just started to look up, is diagnosed with leukemia. With the support of her family and best friend, she might just be able to fight it.
- CreatorJulie PlecKevin WilliamsonStarsNina DobrevPaul WesleyIan SomerhalderThe lives, loves, dangers and disasters in the town, Mystic Falls, Virginia. Creatures of unspeakable horror lurk beneath this town as a teenage girl is suddenly torn between two vampire brothers.
- CreatorGreg SpottiswoodStarsEnrico ColantoniSarah AllenSara CanningGriffin Conner returns home after dropping out of medical school. He gets a job as an orderly at the hospital where his father is the chief of staff and his sisters are a nurse and surgeon.
- CreatorDavid CraneMarta KauffmanStarsJennifer AnistonCourteney CoxLisa KudrowFollows the personal and professional lives of six twenty to thirty year-old friends living in the Manhattan borough of New York City.
- CreatorShonda RhimesMichelle LirtzmanStarsEllen PompeoChandra WilsonJames Pickens Jr.A drama centered on the personal and professional lives of five surgical interns and their supervisors.
- CreatorLeila GersteinStarsRachel BilsonJaime KingCress WilliamsNew Yorker and new doctor Zoe Hart accepts an offer from a stranger, Dr. Harley Wilkes, to work in his medical practice in Bluebell, Alabama. She arrives to find that he has died and left half the practice to her in his will.
- CreatorJeff JudahGabe SachsStarsEoin MackenJill FlintBrendan FehrA group of doctors from the Army return to work the night shift at a hospital in San Antonio.
- CreatorMorwyn BrebnerTassie CameronEllen VanstoneStarsMissy PeregrymGregory SmithEnuka OkumaAndy McNally and her friends are out of the academy and must adjust to the challenging life of a police officer at the 15th Division in Toronto.
- CreatorJanet TamaroStarsAngie HarmonSasha AlexanderJordan BridgesDetective Jane Rizzoli and Chief Medical Examiner Dr. Maura Isles team up to solve crimes in Boston.
- CreatorJulie PlecStarsJoseph MorganDaniel GilliesClaire HoltA family of power-hungry thousand-year-old vampires look to take back the city that they built and dominate all those who have done them wrong.
- CreatorAndrew MillerStarsBritt RobertsonThomas DekkerPhoebe Tonkin16 year old Cassie Blake moves to Chance Harbor, Washington to live with her grandmother after her mother mysteriously dies. She discovers she's a witch along with 5 other teens.
- CreatorMike KelleyStarsMadeleine StoweEmily VanCampGabriel MannAn emotionally troubled young woman sets out to exact revenge against the people who wronged her father.
- CreatorWhitney CummingsMichael Patrick KingStarsKat DenningsBeth BehrsGarrett MorrisTwo young women waitressing at a greasy spoon diner strike up an unlikely friendship in the hopes of launching a successful business - if only they can raise the cash.
- CreatorCraig SilversteinStarsMaggie QShane WestLyndsy FonsecaA rogue assassin returns to take down the secret organization that trained her.
- CreatorJosh SchwartzStarsMischa BartonAdam BrodyPeter GallagherA troubled youth becomes embroiled in the lives of a close-knit group of people in the wealthy, upper-class neighborhood of Newport Beach, Orange County, California.
- CreatorDana KleinStarsJames Van Der BeekMajandra DelfinoZoe Lister-JonesA comedy centered around six 30-something friends who each think the other has it better.
- CreatorElizabeth MeriwetherStarsZooey DeschanelJake JohnsonMax GreenfieldAfter a bad break-up, Jess, an offbeat young woman, moves into an apartment loft with three single men. Although they find her behavior very unusual, the men support her - most of the time.
- CreatorCarter BaysCraig ThomasStarsJosh RadnorJason SegelCobie SmuldersA father recounts to his children - through a series of flashbacks - the journey he and his four best friends took leading up to him meeting their mother.
- CreatorMark SchwahnStarsChad Michael MurrayJames LaffertyHilarie Burton MorganHalf-brothers Lucas and Nathan Scott trade between kinship and rivalry both on the basketball court and in the hearts of their friends in the small, but not so quiet town of Tree Hill, North Carolina.
- CreatorMichael BrandtDerek HaasStarsTaylor KinneyChristian StolteEamonn WalkerThe story of firefighters and paramedics in the city of Chicago, both on a personal and professional level.
- CreatorJ.J. AbramsJeffrey LieberDamon LindelofStarsJorge GarciaJosh HollowayYunjin KimThe survivors of a plane crash are forced to work together in order to survive on a seemingly deserted tropical island.
- CreatorChristopher MurpheyStarsDana DelanyJeri RyanGeoffrey ArendMedical examiner Megan Hunt's unique approach to solving crimes puts her at odds with her superiors.
- CreatorGreg BerlantiMarc GuggenheimAndrew KreisbergStarsStephen AmellKatie CassidyDavid RamseySpoiled billionaire playboy Oliver Queen is missing and presumed dead when his yacht is lost at sea. He returns five years later a changed man, determined to clean up the city as a hooded vigilante armed with a bow.
- CreatorJason RothenbergStarsEliza TaylorBob MorleyMarie AvgeropoulosSet 97 years after a nuclear war destroyed civilization, when a spaceship housing humanity's lone survivors sends 100 juvenile delinquents back to Earth, hoping to repopulate the planet.
- CreatorMeredith AverillStarsAimee TeegardenMatt LanterGrey DamonAbout an epic romance between a human girl and an alien boy when he and others of his kind are integrated into a suburban high school 10 years after they landed on Earth and were consigned to an internment camp.