In Saints Row you start as a member of the 3rd Street Saints, a gang that is under attack from three other gangs that dominate the city of Stilwater. In order to survive, you have to take over their strongholds, and kill the gang kingpins.
Niko Bellic comes to Liberty City, America to live the good life, but ends up having to assist his dangerously indebted cousin Roman with his financial troubles, by any (mostly illegal) means necessary.
An outgoing, sexually aggressive young woman meets and begins a torrid affair with an equally aggressive young man in which their affair begins to bring a strain on their personal lives.