Derek & Meredith
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- DirectorPeter HortonStarsEllen PompeoSandra OhKatherine HeiglThe first shift for new surgical interns Meredith, Cristina, Izzie, George, and Alex proves eventful and backbreaking.
- DirectorPeter HortonStarsEllen PompeoSandra OhKatherine HeiglA rape victim is admitted, who managed to hold onto part of her attacker; Izzie has difficulty with a patient who cannot speak English; Meredith becomes concerned about a sick baby.
- DirectorDarnell MartinStarsEllen PompeoSandra OhKatherine HeiglIzzie and George find out about Meredith and Derek, while Cristina makes a discovery of her own. George thinks an anesthesiologist is drinking on the job, and Meredith deals with a young girl who has had illegal surgery.
- DirectorWendey StanzlerStarsEllen PompeoSandra OhKatherine HeiglGeorge finally gets laid but gets syphilis. It's rampant among staff. Surgeon Webber is losing his sight. He wants Shepherd to operate secretly. A male patient has an ovary. A lifesaving autopsy's performed without consent.
- DirectorPeter HortonStarsEllen PompeoSandra OhKatherine HeiglMeredith, shattered by revelations, is forced to work with Addison, Joe collapses at the bar, Cristina has some pretty shattering news of her own, and Alex starts working on Izzie.
- DirectorAdam DavidsonStarsEllen PompeoSandra OhKatherine HeiglMeredith is horrified when her mother is admitted, and everyone is concerned when Cristina collapses in the operating room. Meanwhile, Addison is determined to save a very sick baby.
- DirectorMark TinkerStarsEllen PompeoSandra OhKatherine HeiglA storm rages, causing power outages and jamming the elevator, trapping George and Alex inside with a vulnerable patient. Meanwhile, Meredith and Derek arrange a religious ritual for a young woman, and Cristina deals with an unusual case.
- DirectorJeff MelmanStarsEllen PompeoSandra OhKatherine HeiglA train wreck brings in multiple casualties, leaving Meredith hanging for her answer. Meanwhile, Alex finds working without his mojo a disheartening experience, and Cristina searches high and low for a missing appendage.
- DirectorLesli Linka GlatterStarsEllen PompeoSandra OhKatherine HeiglFriends of Derek and Addison come from New York for a preventative surgery that causes discord among both couples. Meanwhile, George helps a man who has fallen from a roof, and Bailey delivers news to the Chief.
- DirectorDavid PaymerStarsEllen PompeoSandra OhKatherine HeiglThe nurses are striking, and George refuses to cross the picket line. The interns are surprised by Bailey's seemingly immature replacement, Izzie connects with a pregnant girl, and an elderly woman's plight pushes Meredith to the limit.
- DirectorPeter HortonStarsEllen PompeoSandra OhKatherine HeiglThe lives of everyone in the OR are threatened when a patient enters with a bomb inside him, and a young paramedic with her arm inside the cavity is the only thing keeping it from going off.
- DirectorPeter HortonStarsEllen PompeoSandra OhKatherine HeiglWhile the man with the bomb lodged in his chest remains in Burke's OR with Meredith's hand in the cavity, Bailey's injured husband remains in Derek's. Meanwhile, Bailey's distress puts her unborn baby at risk.
- DirectorDaniel MinahanStarsEllen PompeoSandra OhKatherine HeiglThe victims of a workplace shooting are admitted. Izzie puts her job on the line to ensure Denny gets a new heart, Callie makes an effort with Meredith, and Addison is suspicious of Derek.
- 2005– 1hTV-149.0 (1.9K)TV EpisodeDirectorRob CornStarsEllen PompeoSandra OhKatherine HeiglBurke is admitted as a patient, along with Richard's niece. Izzie and the others fight to keep Denny alive, while Alex tries to secure the donor heart for him.
- DirectorMark TinkerStarsEllen PompeoSandra OhKatherine HeiglRichard is determined to discover the guilty party, and punishes the interns by making them arrange a prom for his niece. Meanwhile, Callie presses George about his feelings, and Derek and Meredith have to make a decision about Doc.
- DirectorDaniel MinahanStarsEllen PompeoSandra OhKatherine HeiglEveryone reminisces about the past. Meanwhile, Izzie is emotionally devastated, with the others trying to help her, Adele gives Richard an ultimatum, and George and Derek are put in quarantine when an outbreak of the plague is suspected.
- DirectorDan LernerStarsEllen PompeoSandra OhKatherine HeiglMeredith becomes a patient, and Derek and Addison are equally angry at Richard for allowing Mark to join the staff. Meanwhile, Izzie receives a visit from Denny's father, and Burke is plagued by doubt over his ability to return to surgery.
- DirectorDaniel MinahanStarsEllen PompeoSandra OhKatherine HeiglDerek, George, Alex, Burke, Richard, Joe and Walter go on a camping trip. Meanwhile, Meredith assists Mark with gender reassignment surgery, Izzie avoids discussing her grief, Addison works with Callie, and Cristina feels Bailey's wrath.
- DirectorJeff MelmanStarsEllen PompeoSandra OhKatherine HeiglGeorge must deal with his family's presence when his father is admitted. Meanwhile, Burke's secret is almost out, Alex tries to get close to Izzie again, and Richard comes to a decision about his marriage.
- DirectorJulie Anne RobinsonStarsEllen PompeoSandra OhKatherine HeiglA traumatic car accident fills the ER. Cristina has a crisis of conscience about her deceptive teamwork with Burke, Izzie pushes the boundaries of her probation, and Callie tries to explain herself to George.
- DirectorJulie Anne RobinsonStarsEllen PompeoSandra OhKatherine HeiglA toxic patient wreaks havoc. Meanwhile, Bailey opens the free clinic, but the lack of patients makes Izzie question her investment. Meredith's mother is admitted again, and Cristina makes Burke wait for an answer.
- DirectorRob CornStarsEllen PompeoSandra OhKatherine HeiglThe interns each react differently to a mass-casualty incident. Meanwhile, George crosses the professional line with Callie, Cristina asks Burke to keep quiet about their engagement, and Richard dons a new hairstyle.
- DirectorRob CornStarsEllen PompeoSandra OhKatherine HeiglIzzie fights to save her patient's life, George searches for the son of his patient, and Alex has to contend with the relatives of victims. Meanwhile, Meredith is unconscious underwater, with Derek her only hope.
- DirectorAdam ArkinStarsEllen PompeoSandra OhKatherine HeiglAn unconscious Meredith interacts with some ghosts from her past while Richard, Burke and Bailey devise an unusual method of reviving her. A despondent Cristina leaves during her shift, and Derek speaks his mind to Meredith's mother.
- DirectorTom VericaStarsEllen PompeoSandra OhKatherine HeiglThe Chairman of Seattle Grace's board of directors is admitted, and the attendings vie for his favor, while the interns study for exams. Izzy and George are reminded of their infidelity, and Burke presses Cristina about wedding plans.
- 2005– 1hTV-146.9 (1.6K)TV EpisodeDirectorMichael GrossmanStarsEllen PompeoSandra OhKatherine HeiglAddison heads for warmer climate to figure things out, Meredith's stepmother visits the clinic, Cristina's perfect wedding is challenged when she and Burke's mothers visit, and Izzie tries to talk to George.
- 2005– 1hTV-147.2 (1.4K)TV EpisodeDirectorMichael GrossmanStarsEllen PompeoSandra OhKatherine HeiglAddison is pulled into the case of a high-risk surrogate mother, Meredith's stepmother develops a complication, Izzie struggles with George's decision, and Ava has surgery which may restore her memory.
- DirectorRob CornStarsEllen PompeoSandra OhKatherine HeiglThe wedding day arrives. Richard chooses the new Chief and Chief Resident, the interns receive their exam results, Callie drops a bombshell on George while Izzie pours her heart out to him, and Burke makes an important decision.
- DirectorRob CornStarsEllen PompeoSandra OhKatherine HeiglThe interns, now residents, deal with their own crops of interns. Callie struggles with her new position, and Burke makes a decision.
- DirectorMichael GrossmanStarsEllen PompeoSandra OhKatherine HeiglAn accident in the ER bay leaves two paramedics fighting for their lives, and a third who refuses Bailey's care. Meanwhile, Alex juggles two women, and Lexie begins to bond with a patient.
- DirectorJessica YuStarsEllen PompeoSandra OhKatherine HeiglTragedy abounds for everyone at Seattle Grace as they all continue in efforts to get the paramedic out of the overturned ambulance, stop the bleeding of a man who won't quit, and a bigot with a Nazi tattoo on his stomach. On the personal side, Rebecca returns to spend time with Alex, Miranda's husband finds it harder to wait for her while she's in surgery, and Cristina still tries to get on Hahn's good side, even though Bailey has put her elsewhere.
- DirectorJohn TerleskyStarsEllen PompeoSandra OhKatherine HeiglBailey's son comes to the ER, Derek takes a housing step that puts pressure on Meredith, Izzie has a crisis of faith, and Cristina's choice may change her course with Hahn.
- DirectorRob CornStarsEllen PompeoSandra OhKatherine HeiglThe judgment of the residents is skewed by a competition, Meredith tries therapy and a bear attack may be more than it appears.
- DirectorMark TinkerStarsEllen PompeoSandra OhKatherine HeiglAddison is not prepared for all the changes that greet her upon her return to Seattle Grace for a specialized surgery, Meredith and Derek begin their clinical trial, Izzie feels left out, and Karev is confronted with an unexpected announcement.
- DirectorRob CornStarsEllen PompeoSandra OhKatherine HeiglA surgical team battles the clock as they try to save a boy encased in cement, Karev's situation with an ever-disintegrating Ava brings back painful memories that interfere with his judgment, Derek and Meredith have one last chance at their clinical trial.
- DirectorRob CornStarsEllen PompeoSandra OhKatherine HeiglMeredith and Derek are at odds over whether or not to continue with their 13th clinical trial patient and the doctors lift the final critical pieces of cement from the young boy's body. Meanwhile, Alex rushes Ava into the hospital and is forced to confront the reality of her condition.
- 2005– 1hTV-148.1 (1.4K)TV EpisodeDirectorRob CornMichael PressmanStarsEllen PompeoSandra OhKatherine HeiglMeredith and Derek find that "happily ever after" isn't as easy as they hoped, Cristina finds interest in a military doctor, and the Chief is surprised to hear that Seattle Grace is no longer ranked as a top-tier teaching hospital.
- 2005– 1hTV-148.2 (1.1K)TV EpisodeDirectorRob CornMichael PressmanStarsEllen PompeoSandra OhKatherine HeiglAs a group of best friends deal with the aftermath of their car crash, Dr. Torres takes the lead on a groundbreaking course of treatment for one of the patients. Meanwhile, Major Hunt starts to irritate other attendings with his presence in the hospital.
- DirectorRandy ZiskStarsEllen PompeoSandra OhKatherine HeiglBailey's dream of a domino surgery crumbles when one of the donors learns of her husband's affair. Meredith is insulted when she gets no credit for the procedure she and Derek worked on together.
- DirectorRob CornStarsEllen PompeoSandra OhKatherine HeiglDerek has trouble with objectivity concerning his death row patient, Cristina and Meredith continue their feud, Izzie confides her problem to Alex, and the Chief faces what's become of his life's work.
- DirectorJeannot SzwarcStarsEllen PompeoSandra OhKatherine HeiglDerek's mother visits, the death row patient starts angling for death in the hospital, Izzie craves more in her relationships, and Jackson's need for organs becomes critical.
- DirectorAllison Liddi-BrownStarsEllen PompeoSandra OhKatherine HeiglMeredith and Miranda each cross a line, William Dunn regrets his decision and Izzie finally confronts what Denny's appearance means.
- DirectorJulie Anne RobinsonStarsEllen PompeoSandra OhKatherine HeiglCristina carries on an intense flirtation with Owen, Derek gets advice from everyone on how to propose, Izzie gets some tests done, and Bailey's promotion may stand in the way of a new career possibility.
- DirectorDaniel AttiasStarsEllen PompeoSandra OhKatherine HeiglOwen runs into someone very special from his past. Izzie employs her fellow doctors in a medical game made to help teach the interns. Naomi, Sam and Addison rush Archer to Seattle Grace and meet with Derek and Mark to save his life.
- DirectorMark TinkerStarsKate WalshTim DalyAudra McDonaldAfter suffering a severe asthma attack at Seattle Grace, Sam is treated by Naomi and Bailey who try to determine the cause. Meanwhile Addison assists Derek in a case involving a pregnant woman.
- DirectorRandy ZiskStarsEllen PompeoSandra OhKatherine HeiglAddison and Derek differ on the treatment plan for their patient, Cristina discovers malpractice in high places, Izzie gets bad news, and Mark spectacularly mistimes his confession.
- DirectorJames FrawleyStarsEllen PompeoSandra OhKatherine HeiglDerek's malpractice deposition reveals an unhappy statistic, the interns finally diagnose 'Patient X', Karev stands up to two attendings to save a band geek, and when Webber shuts Miranda out completely she makes a call.
- DirectorJessica YuStarsEllen PompeoSandra OhKatherine HeiglSloane's facial transplant fades to the background as the interns begin squabbling, Bailey's attempts to reach Derek unexpectedly clear surgeons from the hospital, and Cristina juggles her first solo surgery with treating a resistant Izzie.
- DirectorEdward OrnelasStarsEllen PompeoSandra OhKatherine HeiglOwen's PTSD endangers Cristina, Izzie's illness leaves the residents dealing with guilt and anger - at her expense, and Derek's fear causes him to persevere for Meredith's answer.
- DirectorRob CornStarsEllen PompeoSandra OhKatherine HeiglA car crash involving students going to their college graduation takes its toll on the residents in the ER, Derek's wedding gift is uniquely suited for Meredith - even if the oversight is not. Meanwhile, Denny's return has Derek and Bailey searching for the cause, and the results will change the outcome of the day.
- DirectorBill D'EliaStarsEllen PompeoSandra OhKatherine HeiglIzzie is torn over whether to have Derek's proposed brain surgery. A soldier on medical leave asks for a radical operation so he can return to active duty. The Chief tries to lure Bailey back to general surgery with a new toy, and Mark shifts into high gear with major life changes.
- DirectorRob CornStarsEllen PompeoSandra OhKatherine HeiglIzzie's memory problems panic Alex, the team takes care of a John Doe who was hit by a bus, Bailey rethinks her pediatrics fellowship, and the hospital endures losses.
- DirectorEdward OrnelasStarsEllen PompeoSandra OhKatherine HeiglCovering days one through 13, everyone at Seattle Grace fights to save Izzie and George's lives and then deals with the aftermath. Elsewhere, Hunt treats a double amputation, and Arizona has a teen with painful growth spurts.
- DirectorBill D'EliaStarsEllen PompeoSandra OhKatherine HeiglDuring days 20 through 40 the staff continues toward acceptance. Meanwhile, Arizona takes a manipulative step to diagnose her pain patient and Hunt's amputee patient sinks into a deep depression.
- DirectorTom VericaStarsEllen PompeoSandra OhKatherine HeiglThatcher is hospitalized with liver failure, and Meredith fights anger and guilt while deciding her responsibility. Sloan treats an octogenarian who wants an implant. Izzie's interference in Hunt's cancer case may have deadly consequences.
- DirectorChandra WilsonStarsEllen PompeoSandra OhKatherine HeiglWhen Isaac, the hospital lab tech, has an inoperable tumor wrapped around his spine, he turns to Dr. Derek Shepherd to do the impossible, and Derek tests the Chief's authority when Richard objects to moving forward with the risky surgery.
- DirectorRandy ZiskStarsEllen PompeoSandra OhKatherine HeiglMark flies Addison to Seattle to help with a difficult procedure on his pregnant daughter, Sloan. Owen questions Teddy's motives when she assigns Cristina the lead on a complicated surgery, and Derek's suspicions are raised when the Chief recruits Meredith to assist with a high profile operation.
- DirectorDebbie AllenStarsEllen PompeoSandra OhJustin ChambersAlex' brother Aaron comes to Seattle with a hernia and needs a pro bono operation. Having children is on everyone's minds and tensions are high because of it.
- DirectorTom VericaStarsEllen PompeoSandra OhJustin ChambersBailey preps the team with mandatory sensitivity training prior to admitting a 700-pound patient with compounded medical issues, and the case proves to be challenging. Meanwhile Derek has to come face to face with a former patient's husband in a wrongful death deposition, and spending time with a heart patient's daughter opens up some old wounds for Cristina.
- DirectorStephen CraggStarsEllen PompeoSandra OhJustin ChambersSeattle Grace Hospital is hit with a crisis like no other in its history.
- DirectorRob CornStarsEllen PompeoSandra OhJustin ChambersCristina and Meredith's surgical skills are put to the ultimate test.
- DirectorRob CornStarsEllen PompeoSandra OhJustin ChambersDereks near death experience results in reckless behaviour; Meredith has trouble getting cleared for surgery in the wake of the shooting and Cristina & Owen take their relationship to the next level.
- DirectorTom VericaStarsEllen PompeoSandra OhJustin ChambersAfter weeks of concealing the fact she was pregnant and miscarried, Meredith at last tells Derek and is finally cleared to return to her surgical duties in the wake of the hospital shooting spree; Cristina experiences post-traumatic stress disorder in the midst of an operation; and Bailey refuses to let Alex operate until he agrees to have the bullet in his chest removed.
- DirectorMichael PressmanStarsEllen PompeoSandra OhJustin ChambersWhen Derek receives an unexpected and unwelcome visit from his estranged sister, Amelia, issues between the siblings -- both past and present -- come to the surface; the Chief tries to help Alex when he notices that he's refusing to use the elevators after his near-fatal shooting; and Meredith and Derek continue their efforts to ease Cristina back into surgery after her post-traumatic stress.
- DirectorDebbie AllenStarsEllen PompeoSandra OhJustin ChambersNews of the incoming mass causalities after a gunman opens fire at a local college hits the staff hard when they must spring into action, even while their own wounds are still fresh; and Arizona does not receive a warm welcome home at the hospital.
- DirectorTony PhelanStarsEllen PompeoSandra OhJustin ChambersIn a series first, the music that has been at the heart of the show and been beloved by fans comes to life for Grey's Anatomy: The Music Event. A cataclysmic event rattles the doctors of Seattle Grace to the core, as Callie, on the verge of an enormous life-changing moment with Arizona, envisions her hospital and friends as it has never-been-seen before. "Chasing Cars" (Snow Patrol), "How to Save a Life" (The Fray) and "The Story" (Brandi Carlile) are among the songs performed by the cast.
- DirectorChandra WilsonStarsEllen PompeoSandra OhJustin ChambersAs Callie and Arizona's wedding approaches, the couple quickly realize that the day they've been looking forward to is not turning out the way they'd envisioned. Meanwhile Alex continues to make the other residents jealous as he appears to be the top contender for Chief Resident, Meredith and Derek make a decision that will change their lives forever, and Dr. Perkins presents Teddy with a very tempting proposition.
- DirectorTom VericaStarsEllen PompeoSandra OhJustin ChambersAs the official Chief Resident interviews begin, everyone steps up their game in the hopes of impressing Owen. Meanwhile, Meredith anxiously prepares for her first interview with the social worker and Cristina fights for a shot in the operating room.
- DirectorRob CornStarsEllen PompeoSandra OhJustin ChambersWhile Meredith faces the consequences of tampering with the trial Cristina and Owen fight over an unexpected pregnancy.
- DirectorRob CornStarsEllen PompeoSandra OhJustin ChambersMeredith faces the repercussions of messing with the medical trial.
- DirectorTony PhelanStarsEllen PompeoSandra OhJustin ChambersNews of Meredith and Derek's unsteady relationship raises a red flag for Zola's adoption counselor; Alex quickly realizes that he has become the outcast of the group after ratting out Meredith; and Cristina makes a tough decision regarding her unexpected pregnancy. Also, Chief Webber brings Henry in for a last minute surgery, alarming Teddy.
- DirectorChandra WilsonStarsEllen PompeoSandra OhJustin ChambersThe chief makes a decision that shocks everyone at Seattle Grace.
- DirectorAllison Liddi-BrownStarsEllen PompeoSandra OhJustin ChambersTeddy is called away on another case, as Henry is brought in for surgery.
- DirectorRon UnderwoodStarsEllen PompeoSandra OhJustin ChambersTeddy asks Cristina to help with an OR patient.
- DirectorSteve RobinStarsEllen PompeoSandra OhJustin ChambersThe doctors form two teams to operate on conjoined twins.
- DirectorTony PhelanStarsEllen PompeoSandra OhJustin ChambersIn a final attempt to save Erica's life, Amelia arrives at Seattle Grace to beg Derek for help with the gliosarcoma case; Cristina and Owen engage in heated arguments during marriage counseling; Alex realizes that in order to be a good doctor, he'll need to improve his people skills; and Meredith is given a chance to shine when a man enters the ER after getting his hand stuck in meat grinder. Meanwhile, the residents continue to study for their upcoming oral boards.
- DirectorAllison Liddi-BrownStarsKate WalshTim DalyBenjamin BrattCharlotte and Cooper bring Erica to Seattle Grace to speak with Amelia.
- DirectorMark JacksonStarsEllen PompeoSandra OhJustin ChambersA pet lion on the loose gives the hospital some fierce injuries to deal with. Meanwhile, Cristina continues to ignore Owen, Lexie reconsiders her feelings for Mark, Callie has to face Arizona's romantic past with other hospital staff, and Alex starts to feel uncomfortable about his relationship with Morgan.
- DirectorStephen CraggStarsEllen PompeoSandra OhJustin ChambersBefore the Seattle Grace doctors head to Boise to take part in an operation on conjoined twins, the Attendings pressure the 5th years for final decisions on their posts next year. Meanwhile, Arizona must face the reality of her friend's condition and Ben tries to get Bailey to go on a special lunch date.
- DirectorRob CornStarsEllen PompeoSandra OhJustin ChambersAs Meredith, Cristina, Derek, Mark, Lexie, and Arizona face the aftermath of their accident, the doctors back at the hospital face the future that seems to be taking them all in different directions.
- DirectorTony PhelanStarsEllen PompeoSandra OhJustin ChambersEach of the doctors involved in the crash experiences flashbacks that take them back to their time of rescue and explain how they got to where they are now.
- DirectorRob CornStarsEllen PompeoSandra OhJustin ChambersMonths after the plane crash, the doctors at Seattle continue to try and find a new sense of normalcy. With a new set of interns to put through the ringer, the new fellows and attendings get used to their roles while Cristina adjusts to her new life in Minnesota. But the life of one doctor hangs in the balance and it's clear that Seattle Grace Mercy West is not the same.
- DirectorLaura InnesStarsEllen PompeoSandra OhJustin ChambersIt's Arizona's first day back at work and Callie tries to keep things as normal as possible for her. Meanwhile, Bailey argues with Ben over wedding plans and Cristina and Owen continue to struggle with their relationship while Owen faces his first set of meetings about the plane crash.
- 2005– 43mTV-148.0 (1K)TV EpisodeDirectorCherie NowlanStarsEllen PompeoSandra OhJustin ChambersThe survivors receive a final verdict about the plane crash. Meanwhile, Derek continues to undergo rehabilitation on his hand, Cristina and Owen enjoy their new relationship with each other and Richard tried to avoid Catherine's advances.
- DirectorTony PhelanStarsEllen PompeoSandra OhJustin ChambersAs the hospital inches closer to finding a buyer, many of the doctors don't like the new changes being made, causing the crash survivors to consider a crazy idea. Meanwhile, April's relationship with Matthew progresses and she asks Jackson for advice.
- DirectorDavid GreenspanStarsEllen PompeoSandra OhJustin ChambersWith the new Grey Sloan Memorial Hospital up and running smoothly, everyone is happy about the new changes. Meredith worries about the health of her baby while Bailey tries to get the board members to fund her new plan for genome mapping. Meanwhile, Arizona's new prosthetic gives her the confidence to reignite her relationship with Callie. With the help of a patient, Alex pulls some pranks on Jo's new boyfriend and Cristina tries to get involved in groundbreaking cardio research.
- DirectorTony PhelanStarsEllen PompeoSandra OhJustin ChambersWith a major storm rolling in, the hospital is chaotic. When Jason comes into the hospital in critical condition, Alex does everything he can to protect Jo. With Meredith's due date just weeks away, Derek urges her to slow down.
- DirectorRob CornStarsEllen PompeoSandra OhJustin ChambersAs Seattle is plunged into a major storm, Meredith goes into labour. When the hospital loses power, her doctor and all the others are forced to work in the dark. Cristina must perform surgery in almost complete darkness while Arizona, Alex, and Lauren must ward off terrified parents. Then, just outside the hospital, a school bus full of people crashes and flips over, forcing several doctors to rescue its passengers. Cristina finally confronts Owen on his desire to have kids.
- DirectorRob CornStarsEllen PompeoSandra OhJustin ChambersFollowing the storm, a mudslide injures first responders and citizens.
- DirectorChandra WilsonStarsEllen PompeoSandra OhJustin ChambersCallie makes a decision about her relationship.
- DirectorTony PhelanStarsEllen PompeoSandra OhJustin ChambersDerek and Meredith adjust to life at home with their newborn.
- DirectorRob CornStarsEllen PompeoSandra OhJustin ChambersThe doctors put together a fundraising gala.
- DirectorMark JacksonStarsEllen PompeoSandra OhJustin ChambersMeredith struggles to balance her roles as a surgeon and a mother.
- DirectorDavid GreenspanStarsEllen PompeoSandra OhJustin ChambersCallie and Derek collaborate on a brain mapping project.
- DirectorTony PhelanStarsEllen PompeoSandra OhJustin ChambersMeredith and Cristina bicker about their careers; Bailey talks to Ben about him moving back to Seattle; Shane puts himself in a risky situation; Derek receives a life-changing phone call.
- DirectorRob CornStarsEllen PompeoSandra OhJustin ChambersThe doctors face the consequences of the events that took place at April's wedding. Meredith feels betrayed when Derek goes back on a promise, Alex is furious after returning to the hospital and hearing the news about his father, and Arizona and Callie decide whether or not to move forward together. Meanwhile, Bailey realizes she was wrong about the motive behind Ben's decision to move back to Seattle.
- DirectorNicole RubioStarsEllen PompeoSandra OhJustin ChambersThe doctors of Grey Sloan Memorial Hospital succumb to an infection that spreads like wildfire. Cristina deals with a complex case involving siblings and Alex begins to consider his future in the hospital.
- DirectorRob GreenleaStarsEllen PompeoSandra OhJustin ChambersDerek's sister Amelia comes for a visit; Alex confronts Arizona and the rest of the hospital about his decision; Dr Webber finds out the truth about Harper Avery award from Catherine.
- 2005– 43mTV-148.1 (926)TV EpisodeDirectorBill D'EliaStarsEllen PompeoSandra OhJustin ChambersWhile Bailey faces dire consequences for her reckless behavior, Cristina interviews candidates for Dr. Russell's replacement. Alex returns with a motive, disappointment hits Callie and Derek brings forth a shocking proposal to Meredith.
- DirectorBill D'EliaTony PhelanStarsEllen PompeoSandra OhJustin ChambersCristina must head to Zurich soon but she is unprepared to leave behind her life in Seattle. Fear runs amok throughout the hospital as an explosion in a shopping mall results in a mass casualty situation.