- Godmother of Jake Gyllenhaal and Maggie Gyllenhaal.
- Became formally known as The Right Hon. The Lady Haden-Guest of Saling in the County of Essex, when her husband, Christopher, inherited the barony in 1996 on the death of his father.
- When making reservations in exclusive London restaurants at short notice, she gives her name as Lady Haden-Guest, which apparently works better than Jamie Lee Curtis.
- Holds US patent Patent #4,753,647. "A disposable infant garment which takes the form of a diaper including, on its outer side, a sealed, but openable, moisture-proof pocket which contains one or more clean-up wipers."
- Once said that Dan Aykroyd was the best on-screen kisser she ever worked with.
- Daughter of Tony Curtis and Janet Leigh
- Adopted two children with Christopher Guest: daughter Annie Guest (b. December 1986) and daughter Ruby Guest (b. March 1996).
- It was on her suggestion that Halloween H20: 20 Years Later (1998) was made.
- Said in an interview on Good Entertainment, with Michael Medved (2001) that, ironically, horror films terrify her and she prefers not to watch them.
- Has her legs insured for $2 million.
- Survived a secret Vicodin addiction (1989-1999) that almost destroyed her life, during which time even husband Christopher Guest was totally oblivious to her plight. Not until she attended her first recovery meeting in 1999 did she reveal, for the first time, the details of her addiction to her husband and family. Jamie became addicted after being prescribed opiates after minor plastic surgery for her "puffy eyes".
- John Cleese found it amusing that her father, Tony Curtis's real name was Bernard Schwartz. To tease her about this, during the production of A Fish Called Wanda (1988), he had the call sheets refer to her as "Jamie Lee Schwartz.".
- Around the time True Lies (1994) was released, Jamie appeared in a series of commercials for L'Eggs Pantyhose. The company also took out an insurance policy for her legs.
- When she went to pick up her Tesla car with husband Christopher Guest, the technician instructed them to check out the air conditioning and audio controls, each of which maxed out at "11." Apparently Tesla CEO Elon Musk was a huge fan of the film This Is Spinal Tap (1984) and had the controls exclusively customized for the couple.
- Curtis, along with her daughter, is an avid fan of the Warcraft series of video games, especially "World of Warcraft." She and her daughter often participate in gaming conventions, as well as performing cosplay (dressing in full costume as a character from the series, complete with makeup/prosthetics and props), including a memorable turnout as green-skinned orcs at the US premiere of the "Warcraft" movie.
- Saw her future husband Christopher Guest in the issue of Rolling Stone magazine with Cyndi Lauper on the cover. Guest appeared in a promotional photo for the film This Is Spinal Tap (1984) in full costume and makeup as a rock star. She fell in love at first sight of the photo and gave her telephone number to his agent.
- Was named by McCall's magazine as one of the "10 Best Bodies in America" in 1985.
- Was childhood friends with Eric Douglas. He once tried to kiss her while both were sitting in a tree. Curtis then pushed Eric out of the tree; he fell to the ground, which resulted in a hernia that had to be operated on.
- Won a 2003 Grammy nomination in the Best Spoken Album for Children category for her recording of the children's books she has written.
- She told a German magazine that she will retire from making movies and that Christmas with the Kranks (2004) will be her last work as an actress. (November 2004) She was wrong.
- Was asked to cameo in the sequel Scream 3 (2000), but declined.
- During the 1980s, she was engaged to Hollywood production designer J. Michael Riva, the grandson of screen legend Marlene Dietrich. Her godfather was MCA-Universal CEO Lew Wasserman.
- Travels under the nom-de-plume "Rhoda Penmark," named after Patty McCormack's character in The Bad Seed (1956).
- Two of her earliest roles make reference to roles played by her father. She appeared on the television series Operation Petticoat (1977), based on the movie that had starred her father, Tony Curtis. While on hiatus from that show, she was cast in Halloween (1978), in which the detective "Sam Loomis" was named after a character from Psycho (1960), which had starred her mother, Janet Leigh. Also, her father imitated Cary Grant's voice for his role in Some Like It Hot (1959), and worked with Grant himself in Operation Petticoat (1959). Grant's birth name, Archie Leach, was used as the name for John Cleese's character in A Fish Called Wanda (1988).
- She has played the same character (Laurie Strode) in films released in six different decades from the 1970s to the 2020s: Halloween (1978), Halloween II (1981), Halloween H20: 20 Years Later (1998), Halloween: Resurrection (2002), Halloween (2018) and Halloween Ends (2022).
- Younger sister of actress Kelly Curtis. Older half-sister of Allegra Curtis, Alexandra Curtis and Nicholas Curtis.
- She was awarded a Star on the Hollywood Walk of Fame at 6600 Hollywood Boulevard in Hollywood, California on September 3, 1998.
- In the Married... with Children (1987) episode The Poker Game (1987), Al Bundy votes her as having the perfect legs and breasts.
- Appeared in two feature films with mother Janet Leigh - The Fog (1980) and Halloween H20: 20 Years Later (1998).
- Was introduced to her future husband, Christopher Guest, by Halloween II (1981) co-star Leo Rossi through a mutual celebrity softball league.
- Attended the University of the Pacific in Stockton, California.
- Friends with Sigourney Weaver, and Tyra Banks.
- Graduated from Choate Rosemary Hall private school in 1976.
- Was one of the guests at Sandra Bullock's and Jesse James' wedding.
- Her deleted scene from The Adventures of Buckaroo Banzai Across the 8th Dimension (1984) is included on the MGM Special Edition DVD, 2001, as the "Alternate Opening".
- Following a December 2022 feature in New York magazine, "The Year of the Nepo Baby", Curtis referred to herself as an "OG nepo baby" and said, "The current conversation about nepo babies is just designed to try to diminish and denigrate and hurt.".
- Lives in Santa Monica, California and Ketchum, Idaho.
- Her paternal grandparents, Emanuel Schwartz and Helen (Klein), were Hungarian Jewish immigrants. Her maternal grandfather, Frederick/Fred Robert Morrison, had English, Scots-Irish/Northern Irish, German, Swiss-German, and French ancestry, and her maternal grandmother, Helen Lita (Westergaard), was from a family of Danish immigrants.
- Does not like acting in front of a green screen, which is why she has said she will never be in a superhero film.
- Jamie is the only member of her family to have won an acting Oscar. Her parents Tony Curtis and Janet Leigh were respectively nominated just once for The Defiant Ones (1958) and Psycho (1960), but failed to take home the statuette.
- She and Gigi Garner have known each other since they were both 2-years-old and both were cheerleaders in high school.
- Despite being in iconic horror movie roles, does not like watching scary movies because she doesn't like being frightened.
- Was a member of the jury at the Cannes Film Festival in 1992.
- For her win in Everything Everywhere All at Once (2022), becomes the eighth so-called "nepo baby" (the offspring of a famous parent in the business) to win the Oscar for Best Supporting Actress. Those before her are Tatum O'Neal, Vanessa Redgrave, Anjelica Huston, Mira Sorvino, Angelina Jolie, (arguably) Patricia Arquette, and Laura Dern.
- Stated on a featurette to Halloween (2018) that she was originally going to be a police officer before becoming an actor.
- She has appeared in one film that has been selected for the National Film Registry by the Library of Congress as being "culturally, historically or aesthetically" significant: Halloween (1978).
- Sister-in-law of Nicholas Guest and Pamela Guest.
- For years has been the spokeswoman for Activia yogurt.
- Her parents divorced in 1963.
- Is one of 23 actresses who did not receive an Oscar nomination for their Best Actress in a Comedy/Musical Golden Globe-winning performance; hers being for True Lies (1994). The others, in chronological order, are: June Allyson for Too Young to Kiss (1951), Ethel Merman for Call Me Madam (1953), Jean Simmons for Guys and Dolls (1955), Taina Elg and Kay Kendall for Les Girls (1957), Marilyn Monroe for Some Like It Hot (1959), Rosalind Russell for A Majority of One (1961) and Gypsy (1962), Patty Duke for Me, Natalie (1969), Twiggy for The Boy Friend (1971), Raquel Welch for The Three Musketeers (1973), Barbra Streisand for A Star Is Born (1976), Bernadette Peters for Pennies from Heaven (1981), Kathleen Turner for Romancing the Stone (1984) and Prizzi's Honor (1985), Miranda Richardson for Enchanted April (1991), Nicole Kidman for To Die For (1995), Madonna for Evita (1996), Renée Zellweger for Nurse Betty (2000), Sally Hawkins for Happy-Go-Lucky (2008), Amy Adams for Big Eyes (2014), Awkwafina for The Farewell (2019), Rosamund Pike for I Care a Lot (2020) and Rachel Zegler for West Side Story (2021).
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