- Worked as a sign language interpreter at hospitals, where she would be in delivery rooms while babies were born to deaf mothers and fathers.
- Wears 12 earrings in her right ear to beat someone she knew who had 11.
- She has played the same character (Ellenor Frutt) in four different television series: The Practice (1997), Ally McBeal (1997), Boston Public (2000) and Gideon's Crossing (2000).
- She is fluent in American Sign Language (ASL). She fell into it almost by accident, then studied it at Cabrillo College. She has since been able to use it in many roles, including Benevolence (1993), Mercury Rising (1998), and The Practice (1997).
- Changed her name when she was 20 years old.
- Mother of Milo Manheim.
- Received a master's degree in drama in 1987 from New York University.
- MFA in Acting - New York University, Tisch School of the Arts (1987).
- Has a tattoo of Pegasus on her ankle.
- She participated in the Deaf West production of the musical Spring Awakening as 3 separate characters ( Frau Bergmann, Fräulein Großebüstenhalter, and Fräulein Knuppeldick) in 2015, speaking the signed parts by Marlee Matlin and signing her own parts as well.
- Brother, Karl Manheim, is a professor at Loyola Law School in Los Angeles, CA.
- Her book, "Wake Up, I'm Fat!" is a New York Times Best Seller.
- Former model Jeffrey Brezovar is the birth father of her son Milo.
- She teaches and lectures all over the United States.
- Worked as an American Sign Language interpreter at a hospital and as a job trainer for the Deaf.
- She wrote an off-Broadway play, "Wake Up, I'm Fat" in 1995.
- She has played the same character (Lt. Kate Dixon) in three different series: Law & Order (1990), Law & Order: Special Victims Unit (1999) and Law & Order: Organized Crime (2021).
- She is from a Jewish family (from Poland, Germany, and former Czechoslovakia).
- Is an avid Texas Hold Em player.
- She is a lifelong liberal Democrat.
- Casting Director Randy Stone (Twentieth Century and X Files royalty) suggested Camryn Manheim to David Kelly for the role in The Practice.
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