- Was the inspiration for the character of "Dr. Teeth", the band leader of "Dr. Teeth and the Electric Mayhem", on Jim Henson's The Muppet Show (1976).
- He was originally a guitar player, but after getting his index finger nearly shot off in an effort to protect band mate and friend Ronnie Barron, he switched to piano/keyboards.
- Inducted into the Rock & Roll Hall of Fame on March 14, 2011. The other inductees were Darlene Love, Neil Diamond, Alice Cooper, Leon Russell and Tom Waits.
- Was inducted into the Louisiana Music Hall of Fame in 2007.
- Mentioned in the song "Life Is a Rock But the Radio Rolled Me" by Reunion.
- He was the son of Dorothy (Cronin) and Malcolm John Rebennack. His ancestry included German, Irish, Spanish, English, and French.
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