- Committed suicide using ant paste.
- Credited with inventing the first automobile turn and brake signals. The signals were operated by the driver pressing a button, and an arm on the back of the car indicating the turn direction or a stop. She did not patent the inventions, and they were superseded by more streamlined systems.
- When she left Biograph for IMP, Biogaplh falsely reported that she had died. IMP's head, Carl Laemmle countered on 3/3/1910 with the now-famous headline "WE NAIL A LIE." When the Patents Company found that a particular theater was showing an IMP film, it lost its right to show any films produced by the monopolistic Trust.
- Fired from Biograph when she was discovered to be negotiating with Carl Laemmle of Independent Motion Picture Company.
- Entered films with Vitagraph in 1907.
- The birth date on her gravestone is 1890, but many sources say 1886.
- In the early 1900s she was officially known as the "Biograph Girl" for the American Mutoscope & Biograph Co.
- Fulfilled her lifelong dream of buying a large ranch in New Jersey where she gardened and had a collection of animals.
- Subject of the novel "The Biograph Girl" (2000) by William J. Mann, who imagines Lawrence didn't die in 1938 from ingesting ant poison and is still alive in the late 1990s.
- Her mother, Charlotte "Lotta" Dunn Bridgwood, was an Irish-born vaudevillian who acted professionally under the name "Lotta Lawrence", which was the source of Florence's stage name. Lotta's company, the Lawrence Dramatic Company, operated in the Hamilton, Ontario. area. Florence made her stage debut with the company sometime around her fourth birthday. She was an accomplished whistler who had earned the nickname "Baby Flo, the Child Wonder Whistler" by the time she was six years old.
- Lawrence's grave at Hollywood Memorial Park (now Hollywood Forever) was unmarked for over 50 years. In 1991 a bronze plaque was donated by an anonymous British actor; according to some sources the donor was Roddy McDowall. Lawrence's epitaph reads, "'The Biograph Girl' - The First Movie Star".
- In 1937 Lawrence became one of the so-called "Old-Timers", a group of aging, neglected former stars who were employed as $75-a-week extras by MGM as an act of charity. At 1 p.m. on December 28, 1938, Lawrence phoned the studio to say she was too ill to work that afternoon. She then took her own life.
- While filming The Pawns of Destiny (1914) Lawrence suffered a spinal injury and burns in an accident on the set. She never fully recovered, and her subsequent health problems led to the gradual decline of her career.
- Lawrence fatally poisoned herself in her duplex apartment at 532 Westbourne Avenue in West Hollywood, CA. As of 2022 the house is still there, though the front is now hidden behind a tall hedge.
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