- Irene Santiago was actually pregnant whilst performing in the show, "High School Musical".
- Irene Santiago was once a magician's assistant and a singing telegram and went under the stage name, "Santiago.".
- Did you know that Irene Santiago never broke character while filming Providence? She played a stroke victim and stayed in character between takes.
- During the filming of The Penthouse, shot in North Carolina. In a particular scene with Irene Santiago and Michael Pare, the scene was shot in the pouring rain, because hurricane Dorian was scheduled to hit land in just a few short hours. The film crew and actors were drenched. They wrapped 2 hours before the storm hit. Everyone was safe.
- Irene is known for her big, dark eyes.
- Irene was 2nd Runner Up in Miss Hispanic 1984.
- When she was 18, Irene was part of a High School Drill team that had the opportunity to perform on a cruise line.
- Irene Santiago was a cheerleader in 8th and 9th grade when she was attended Kearns Jr. High in Kearns, Utah.
- While doing a singing telegram gig, an agent saw her act and signed her up.
- Irene Santiago was really pregnant when she was cast in High School Musical 1.
- Irene Santiago, co-executive produced the award-winning faith-based film, Adrenaline and she played the race track reporter, Diane Godwin, in the film.
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