- She is related (via marriage) to former Speaker of the House Paul Ryan. Her husband's (Patrick G. Jackson) twin brother, William, is married to Paul's sister-in-law, Dana.
- On February 25, 2022, President Joe Biden nominated her to become the 116th Associate Justice of the United States Supreme Court. She was confirmed by a 53-47 vote of the U.S. Senate on April 7, 2022, making her the very first black woman to sit on the Supreme Court. She is also the first public defender the sit on the United States Supreme Court.
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