The character of E.K. Hornbeck in "Inherit the Wind" was modeled after him. The role has been played by, among others, Gene Kelly, Darren McGavin, and Beau Bridges.
Was the lead reporter at the infamous Scopes Monkey Trial.
Mencken was an outspoken defender of freedom of conscience and civil
rights, and an opponent of persecution, injustice, puritanism, and
self-righteousness.
The address of his family home in Baltimore was 1524 Hollins
Street.
He was both superstitious - regarding such familiar symbols as the
number 13 - and a hypochondriac: he befriended many Baltimore
physicians and was a frequent visitor to, though not as a frequent
patient with serious maladies, the corridors of the city's Johns
Hopkins Hospital.
Edited two magazines in New York with drama critic George Jean Nathan while
commuting to and from Baltimore where he kept up his column at the
Baltimore Sun. The first magazine was The Smart Set, the second The
American Mercury, in which Mencken brought to attention dozens of
writers destined for fame.
The doctor who delivered him charged his parents a flat $10.00 for handling the birth.