- Co-invented and, with his Magic Introduction Co,, marketed the Magic Pocket Lamp, the world's first cigar lighter. He sold the patent rights to the Ronson Company to help fund the newly formed film production company American Mutoscope & Biograph.
- On December 28, 1895, he co-founded the American Mutoscope Company, later to become American Mutoscope & Biograph Co., popularly known as "American Biograph" or just "Biograph." Over the next two decades many of the biggest names of the silent screen would get their first movie jobs at Biograph, including D.W. Griffith, Mary Pickford, Mack Sennett, Blanche Sweet, Lionel Barrymore, Lillian Gish, Dorothy Gish and Florence Lawrence. The company is still in existence and is the oldest movie company in America, and continues to perpetuate the history and dreams of William K.L. Dickson and its other founders.
- Co-founded K-M-C-D Syndicate, a production company, in Chicago in 1894. It was reorganized later that year as the American Mutoscope Co.
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