- He died at Cedars-Sinai Medical Center where he was director of the Medical Genetic Institute since 1986 to 2012.
- He earned his medical degree from McGill University in Montreal, Quebec, Canada. He studied at John Hopkins University in Baltimore, Maryland under Dr. Victor McKusick, He earned his Ph.D. in human genetics in 1967 from John Hopkins University. He later worked at Washington University in St. Louis, Missouri and Harbor-U.C.L.A. Medical Center.
- At his death, he was working with Dr. Kaback on providing genetic testing for four inherited disorders most likely to occur in Persian Jews including one that involve unusual sensitivity to anesthesia.
- He lived in Beverly Hills, California. He is survived by his wife, Ann Rimoin; his daughters, Annie Rimoin and Lauren Rimoin; a son, Michael Rimoin; two sisters, Shirley Rimoin Entis and Mona Rimoin Deutsch.
- He earned an honorary lifetime membership in Little People of America founded by friend, Billy Barty. His patients included entertainers with dwarfism and other growth disorders. He also treated Rocky Dennis. HE also pinpointed genetic defects that caused particular skeletal or growth disorders.
- He studied the pygmies in Central Africa in the 1960s.
- He was a student of genetics not long after James D. Watson and Francis Crick deduced the structure of DNA.
- He was also the first to suggest in the 1960s that diabetes was not one disease but one with multiple forms.
- In 1970, he co-founded the international registry of cases to help identify and diagnose inherited skeletal dwarfism.
- In the 1970s, he and Dr Kaback developed the first large scale screening program for Tay-Sachs disease.
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