- Defender for Ferro Carril Oeste (1991-1993), River Plate (1994-1995), S.S.C. Napoli (1995-1998), A.C. Milan (1998-2000), Valencia C.F. (2000-2007), Villarreal C.F. (2007), Real Zaragoza (2007-2010) and Racing Club de Avellaneda (2010).
- Has a daughter called Cinthia born in 1990.
- Honours with River Plate: Argentine League (1994). Honours with Milan: Serie A (1999). Honours with Valencia: La Liga (2002, 2004), UEFA Cup (2004), UEFA Super Cup (2004).
- Honours with Argentina's youth teams: Pan American Games (1995 gold medal) and Olympic Games (1996 silver medal, 2004 gold medal).
- Father of, with Verónica, Francisco Ayala, Sofía Ayala, Pilar Ayala and Martina Ayala.
- 115 appearances for Argentina National Football Team (1994-2007); scored 7 goals. Member of the Copa América 1995, 1999, 2004, 2007, and the France '98, the Korea/Japan '02 and the Germany '06 squads.
- Named in the South American Team of the Year in 1994.
- Member of the Argentine National team who finished runners-up of the King Fahd Cup (1995) and the Copa América (2004 and 2007).
- Won the UEFA Club Football Award for "Best Defender" in 2001.
- Named in the European Sports Media Team of the Year 2003-04.
- Named in the All-Star Team of the 2006 FIFA World Cup.
- Retired from football at the age 37. (December 2010)
- Ballon d'Or nominee in 2004.
- Played well over 250 games for Valencia C.F..
- Played well over 100 games for Argentina National Football Team.
- Played well over 100 games at Argentine Primera División, Serie A and La Liga.
- Manager of Racing Club de Avellaneda (2010-2012) and Valencia C.F. (2013-2016).
- Played for Argentina at the 2018 FootGolf World Cup.
- Member staff of the coach Lionel Scaloni since 2019.
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