- Head coach of Juan Aurich (2002), Sport Boys (2002-03), Coronel Bolognesi (2004-06), Sporting Cristal (2007), O'Higgins F.C. (2007-09), C.S. Emelec (2010), Club Universidad de Chile (2011-12), Chile National Football Team (2012-16), Sevilla F.C. (2016-17), Argentina National Football Team (2017-18), Santos F.C. (2018-2019), Atlético Mineiro (2020-2021) and Olympique de Marseille (2021-).
- Started as coach in Argentine amateur league in 90s.
- Led Club Universidad de Chile to win three Chilean leagues (2011 Apertura, 2011 Clausura, 2012 Apertura) and the first international cup (2011 Copa Sudamericana).
- Led Chile National Football Team to finished 3rd place in the 2014 FIFA World Cup qualification (CONMEBOL). The team was eliminated in the Round of 16 by Brazil National Football Team.
- Led Chile National Football Team to win the first Copa América title in their history in 2015.
- In 2015 he was awarded the 'World's Best National Coach' by IFFHS and the 'South American Coach of the Year' by Uruguayan newspaper El País.
- Father of Sabrina Sampaoli and Alejandro Sampaoli.
- Won the award "AS América" in 2016.
- Led Argentina National Football Team to finished 3rd place in the 2018 FIFA World Cup qualification (CONMEBOL). The team was eliminated in the Round of 16 by France National Football Team.
- Father of, with Paula Velásquez, León Sampaoli (b. September 16, 2019).
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