Caroline and her husband, Luke Bryan, were college sweethearts.
Her infant niece, Sadie Brett (born in the summer 2016), died on February 21, 2017, after battling undisclosed cardiac issues, among several other health problems. Sadie was the daughter of her brother, Bo Boyer, and his wife, Ellen Boyer.
Became pregnant six months into her marriage to Luke Bryan but later suffered a miscarriage.
Mother, with husband Luke Bryan, of two sons named Thomas Boyer Bryan (b. March 18, 2008) and Tatum "Tate" Christopher Bryan (b. August 11, 2010).