A recent episode found a group a group of comedy writers trying to determine which topics were offensive and off-limits.
Jay (Nyambi Nyambi) complained in the show that comedians are held back nowadays by sensitive audiences.
They concluded the off-limit topics should include necrophilia, autism, and "Selena Gomez's kidney transplant."
Fans were, understandably, unimpressed with the shoutout, and a few weeks after the episode aired, Gomez responded on social media.
"I am not sure how writing jokes about organ transplants for television shows has become a thing but sadly it has apparently," she wrote on Twitter.
"I hope in the next writer's room when one of these tasteless jokes are presented, it's called out immediately and doesn't make it on air."
The star shared a link to OrganDonor.gov, where individuals can sign up to donate certain organs to patients in need.