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- Six families who experienced antidepressant drugs prescribed to their children, describe their feelings, reactions, relationships with the medical professionals involved, and how they cope with the challenges resulting from these medications. Many experienced tragedies. Their pain is undeniable, yet with strength, they speak for those who are no longer with us.
- When the staff makes grumblings about their jobs, Kirstie decides to show them who's boss.
- Compelling and fascinating insights into the relationships between death row prisoners and British women. In Britain today, over 100 women are married or engaged to prisoners on America's Death Row.
- Kirstie steps on the scale and reveals her weight to world. After an ugly run-in with the paparazzi, she decides to shed all those excess pounds the tabloids love to feature on their covers.
- Andy fights for the rights to an organ from a liver transplant; Lu helps out a woman whose husband has just been released from prison; Nick treats a paramedic who was stuck with a needle from a drug addict.
- Andy and Milo are invited to stay in a beach-side cabin owned by a patient of Andy's at Cape June, a beach-side vacation community. The vacation gets interrupted when a young boy suddenly becomes very ill with similar symptoms to Andy's patient who has cancer. Andy is further shocked to learn that 9 other residents of the town have died from cancer.
- Kayla competes with a fellow male colleague to get the job of chief resident; Lu deals with a teenaged patient who wants to be emancipated so she doesn't have to donate a kidney to her sister.
- Lu and Dylan face an ethical dilemma when it comes to using an experimental drug on a patient with Parkinson's disease; Lu treats a deaf woman who was injured in an accident; Kayla treats patients from a circus suffering from tuberculosis.
- When elderly patients die under suspicious circumstances, Peter becomes a suspect; Andy treats a judge suffering from hearing loss caused by abusing pain medication.
- When the sister of a famous gymnast is in need of a liver transplant, Lu faces issues with her family who refuse to help; Kayla and Andy become concerned after a depressed resident attempts suicide.
- Lu contemplates whether or not she should recommend a clinical trial for an experimental anti-smoking drug to her patients.
- After a young adult film star is diagnosed with an STD, Lu tries to find out how she contracted the disease; Andy seeks to gain the position of chief of surgery; Kayla treats a teenage boy with a gunshot wound.
- Lu is concerned about the health of a female boxer who suffered from a serious concussion; as she copes with her impending divorce, Andy faces a serious health crisis.
- Marc seeks Lu's help with a friend of his who is being physically abused by her boyfriend; Andy treats a married couple struggling with obesity who decide to treat their problem surgically.
- At heights of 7 feet, even 8 feet plus, giants really do walk the earth. We'll use cutting edge animation to go inside the extraordinary bodies of giants to unlock the secrets of their unique design and the multiple causes of their astounding height. Igor Vovkovinsky is, by any measure, monumental. This 24-year old immigrant from the Ukraine stands a whopping 7 feet 8 inches tall. Igor came to America in search of help to stop his incredible growth. The doctors soon found that Igor has pituitary gigantism, a condition usually caused by a benign tumor on the pituitary gland, located at the base of the brain behind the eyes. We go inside Igor's extraordinarily large body and compare it to an average size man to see just how this "master gland" controls height through the release of Human Growth Hormone or HGH. We'll also meet Sandy Allen, a 51-year old who holds the Guinness Book of World Records' title as the tallest living woman. Sandy is 7 feet, 7¼ inches tall, and has acromegalic gigantism. Though she stopped growing taller long ago, the continued surge of growth hormone associated with acromegaly has restructured her body in distinct and often painful ways. We leap inside her massive skeleton to see how growth hormone produces prominent brow ridges, thick jaws and enormous hands and feet that are out of proportion with the rest of the body. And it's not just the skeleton that is affected by a giant's incredible growth. Sandy's internal organs are twice the size of those of average people but that doesn't mean they work twice as well. From heart and lungs, to vocal chords, to the way their nerves deliver signals, we see how giant bodies are not necessarily giant performers. We'll also meet 7 feet, 3¾ inch tall, Dave Rasmussen, an IT professional and amateur musician. Dave's form of gigantism is not caused by a tumor. Dave has a rare genetic syndrome called MASS Phenotype, which sometimes results in gigantic stature. Inside Dave's body, we see that this syndrome produces a much different type of giant from Igor or Sandy. Dave is exceptionally lean, with a narrow skull and arms and legs that appear disproportionately long for his trunk. Although scientists are looking to find ways to prevent pituitary tumors, early detection and removal are still the best method to limiting final adult height and avoiding the sometimes life-threatening medical conditions associated with gigantism. But for pituitary giants who have already reached their full, breathtaking height, there is no turning back. Currently, there is also nothing that will prevent genetic forms of gigantism. So, for now, there will continue to be giants in the world, living life on a higher plane.
- Lu treats a young college woman with meningitis; meanwhile, Dana develops symptoms which suggest that she might be pregnant.
- Lu discovers that two teenage girls have been poisoned by a girl at their high school they have bullied; a patient of Andy asks her to endorse her new heart-health diet book only to end up in the emergency room suffering from a heart attack.
- Andy diagnoses a woman with West Nile virus; Lu tries to help out a woman and her hospital-bound son.
- Lu's past comes back to haunt her after her rapist, Dr. Kilner is brought to the emergency room with heart issues.
- Dana treats a former high school rival who is diagnosed with a brain tumor; an ER nurse plans to sue the hospital after contracting HIV from a patient.
- Dana treats a pro-life politician diagnosed with preeclampsia; Lu treats a woman who is undergoing menopause.
- Lu helps out a mother who has been diagnosed with Alzheimer's that is in danger of losing custody of her teenage Down Syndrome son; Dana is concerned about the welfare of a pregnant alcoholic woman.
- Lu fears the worst when an abused pregnant patient of hers disappears; Andy clashes with a chauvinistic doctor whose behavior causes a misdiagnosis in a teenage girl.
- Dr. Campbell treats Rachel, a patient she believes is an alcoholic but she won't admit to her drinking problem. The patient's daughter Jordan goes to desperate measure to get her mom to stop drinking. Another of Andy's patients needs to get a kidney transplant but nobody in her family is a match. Tammy's mom then reveals a horrible secret that could save her daughter's life - she was raped and her daughter is the product of that rape. Meanwhile, Lu, Lana, Peter, and Ben go out on the streets to find out what is threatening the lives of young infants.
- Andy treats a female soldier with post-polio syndrome; Lu becomes attracted to a patient's son.
- Dylan helps out a woman who underwent a mastectomy whose insurance company wants her to be released from the hospital 24 hours after her surgery; Lu finds herself caught in the middle of a woman with cerebral palsy who sues her mother for negligence.
- A nurses' strike affects the hospital which forces Dana to withhold an experimental treatment for a sick baby and delays a medical procedure for an abused patient of Lu's.
- A businessman offers a big donation to the women's health center; Andy's financial issues affect Jesse's upcoming Sweet 16 party.
- Dana treats a male acquaintance of hers who is diagnosed with cancer; Lu gets in trouble with the police after defending a diabetic woman who was mistaken as being a drunk driver.
- In the middle of a crushing heat wave, Andy is confronted with the ethical dilemma of whether to help a single woman, pre-destined to have early Alzheimer's disease, have a baby. Also, Lu fights to save a sixteen-year old girl who has been shot in a gang initiation and finds out the truth about a mother who turns in her daughter with Downs Syndrome as the perpetrator of the shooting. Andy struggles with introducing Dr. Milo Morton to her daughters. Elsewhere, Andy and Milo stop a baby's heart in the fight to save its life.
- After Mickey is shot by a mentally ill patient of Lu's, Lu faces a difficult decision whether or not she should keep him on life support or donate his organs to be transplanted; Andy treats a woman who is in need of a heart transplant and tries to help out the parents of a infant son who has a genetic disease.
- Jesus "Chuy" Aceves, also known as the Wolf Boy, wants regular job, outside of the circus or sideshow.
- Dr. Andy Campbell joins the Rittenhouse Women's Health Center as Lu's new partner; on Andy's unofficial first day, she clashes with Lu over a woman who had an illegal kidney transplant and a patient of Lu's who refuses to get her young son vaccinated.
- Lu fears that her unborn child might have a fatal genetic condition and defends a pregnant mother who is accused of welfare fraud.
- A patient of Andy's seeks help to stop her chronic blushing; Lu is unsure about whether or not she should prescribe a painkiller to a recovering drug addict.
- Lu helps out a teenage girl who wants to get out of the gang life; Dylan fights to get a young woman with Down Syndrome a heart transplant.