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- A young patient confounds doctors when he presents with traditional symptoms of vampirism.
- There is plenty of excitement at the hospital for the opening of the day care center. However, the excitement is short-lived when a child is injured in a fall and it is found out that the day care director was once in a mental institution.
- Performance-enhancing drugs take a serious toll on two athletes. Meanwhile, a pair of birdwatchers take their hobby to the extreme.
- J.T. finds a boy who is suffering from malnutrition living in a dumpster and brings him to San Francisco Memoral for care. His mother arrives to claim him but seems to be in the same strange condition that he is: very violent and without language.
- Against his better judgement, Trapper agrees to staple the stomach of an obese woman. Gonzo goes to unusual lengths to save Andrea's dog.
- Libby is crushed to discover an old boyfriend is both homosexual and suffering from AIDS.
- One of the hospital's doctors brings a mail order bride from the Philippines.
- Gloria finds out Andrea's issues are drug-related. Meanwhile, a homeless woman has been stealing supplies from the hospital.
- Four witnesses give four very different accounts of what happened when an accident victim died at San Francisco Memorial.
- Trapper lets his imagination run wild when vintage medical equipment stored in his office makes him wonder how doctors in 1917 dealt with issues considered routine in the 1980s.
- Neurosurgeon and recent new father Jake Christmas is angry and scared because of his wife's sudden death in a car accident and begins lashing out at Trapper and J.T.
- Slocum tries to put a stop to Jackpot's moonlighting. When the owner of a favored hang-out undergoes surgery, the staff cover her shifts to keep her business afloat until she recovers.
- On a foggy Thanksgiving, Slocum hits Trapper with his car. As John fights for his life, staff members recall (in flashbacks) reasons they have to be thankful for his friendship and help.
- The doctor who left Nurse Andrews at the altar 38 years ago becomes one of her patients for rehab following his heart attack and has never stopped loving her.
- A patient at SFM who fancies himself a detective is determined to solve the mystery of missing medication, to the despair of the police working on the case.
- A cancer patient who dies at the hospital leaves all his worldly wealth to Gonzo, who discovers that most of it was obtained illegally. Jackpot, Ernie and Gloria conspire to trick Stanley into taking his annual physical.
- Talented neurosurgeon Russ Brandis enduring a deadly disease and fits of rage he shows are due to the drugs he must take. The surgeon's personal problems are uncovered as Riverside and Gonzo try to recruit him for the hospital staff.
- A nurse who was paralyzed in an accident returns to work without letting anyone know she is now in a wheelchair. Meanwhile, Jackpot considers becoming a professional musician.
- A former cowboy who's given up on life is fading fast, and it's up to Trapper John to reignite his desire to live.
- A 74-year-old woman who is admitted with a blocked artery in her leg has another problem - she is hooked on prescription medications. When Trapper and Gonzo discover that her doctor is responsible, and treats all his patients the same way, they plot to drive him out of business.
- Gonzo and Trapper try to track down the family of a 10-year old girl who was hit by a car and is exhibiting erratic behavior. The only leads they have are gang members with whom she was living with.
- When Gonzo starts dating a high society woman she tries to convince set up his own private practice and into selling the "Titanic" to Jackpot.
- An emotionally troubled musician is released much too early from the hospital. Nurse Shoop suffers a hearing loss.
- Trapper questions Ernie's motives when she accepts a proposal from a long-time suitor only after she finds out that he is dying.
- When a doctor who is a friend of Jackpot's is dying and she appears to have given up any hope and wants to die. She goes to court asking that she be allowed to die. And the judge presiding over the case is Jackpot's estranged father.
- Vinnie Duncan, Gonzo's good friend, leads a fund campaign for rare-disease drugs.
- When a nurse behaves erratically, Gonzo recognizes it as PTSD. He tries to help her but she refuses to admit that's what's wrong with her.
- An aging singer learns that she's pregnant. Meanwhile, Trapper John looks to secure funding for a laser center at San Francisco Memorial.
- Gonzo's mother introduces him to her new boyfriend, a sportswriter his age. Gonzo is not happy about the situation.
- A young resident is torn between his desire to accept a high-profile medical position and his sense of duty to return home to serve the community that put him through medical school.
- A former hippie suffers a stillborn fetus. A kidnapper brazenly takes the Riversides' son right out of his stroller.
- Gonzo's professional confidence and bedside manner are affected by a malpractice lawsuit, after a young patient asserts that he has begun to feel worse after an emergency operation. A patient is mistaken for a hospital inspector.
- A surgeon dies during a complicated operation. The procedure he used was known only to him. Unless his notes can be found, the patient will die. After seeing the ghost of the deceased doctor, Gonzo frantically tries to locate the notes.
- Gonzo is convinced that the paranoia of one of his patients has a physical cause. Slocum attempts to cut back on nursing costs by employing a robot nurse, who proves to be quite successful.
- Trapper John and Gonzo are captured while at their vineyard. A representative for survivors of nuclear radiation exposure tries to get help from San Francisco Memorial.
- Trapper's busy hospital schedule becomes even more hectic when family problems crowd in. Melanie arrives to inform him the their daughter Kim is planning to drop out of school.
- J.T. discovers that he has two patients with the same wife.
- Trapper runs afoul of a bombastic television reporter when he desperately attempts to revive his seven-year-old niece.
- A baby admitted to the hospital for a urinary tract infection turns out to be a hermaphrodite, sparking a battle between the parents over which sex it should be.
- Trapper fears an epidemic after the leader of a research project becomes mysteriously ill.
- Riverside comes under fire after he takes over one of Gonzo's patients who happens to be dating his father and she ends up almost dying from an allergic reaction to fluorine.
- A mentally disabled man who works at the hospital is able to make friends with a crotchety old hermit who is dying of cancer, but gets embarrassed and quits his job when he misinterprets Gloria's feelings for him.
- A 'bubble boy' needs a bone-marrow transplant to revitalize his immune system.
- After J.T. begins taking care of a well-known rock singer with melanoma, he realizes the man is different than he expected him to be. Meanwhile, Jackpot wins a lottery, but cannot find the ticket to claim the prize.
- The staff are stymied by two suffering patients who have decided to cease treatment and let nature take its course.
- A shy and clumsy nurse asks Trapper for advice on how to attract Gonzo. A woman who is obsessed with her appearance is reluctant to have a tumor in her face removed.
- Trapper John and Gonzo's push to get a gung-ho new doctor on staff at San Francisco Memorial may be derailed by a skeleton in his closet.
- 1979–19861h7.5 (13)TV EpisodeA female prisoner gives birth to a premature baby, who is rushed to SFM for care. The mother, upset at not being allowed to be with her child, beats the prison warden who refused to arrange for her to be taken to the hospital.
- A man who needs a bone marrow transplant to survive claims that he has no relatives that can serve as donors. However, Gonzo soon discovers that the truth is a little more complicated: the man is in the Witness Protection Program, and cannot safely have contact with his family.
- Hub Wendover arrives at San Francisco Memorial Hospital for treatment for his leg and to be close to his son, Gonzo. Trapper operates on Hub finding his body riddled with cancer. Gonzo and Hub have some issues to deal with. Gonzo can't help but love the Father that supposedly walked out when he was four years old.