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- Dirk wants to take Lucy to Rotterdam and confesses he has developed feelings from Reini. A young man lies about his former drinking habit because he needs a liver transplant. Pieter tells Suzanne he wants to start anew with her and will wait for her even if she has to go to jail
- Dr. Paul van der Voort announces his retirement and will choose either Jan vd Woude or Eric Koning to replace him for the time being. Nurse Nelleke is pregnant, which reminds head nurse Reini that it's too late for her to have children. An elderly patient , Mrs Oudenaar, asks the medical staff to let her die peacefully.
- Sonja has died. Eric is told to get rid of all the evidence and point all the blame towards Jan. Liza insists on visiting Victor's grown up autistic son Roelant. Lucie, who is working as a doctors assistant, proves to have a problem with authority. Guus has hit a female colleague with his car and is feeling responsible. This leads to questions from his boyfriend.
- Reini takes the blame for performing euthanasia on Mevr. Oudenaar. When a beat up woman is brought into MCW, domestic violence is suspected. Eric gets a job offer from his father Leo Koning.
- Lucy runs away from home, thinking she has caused trouble between Reini and Dick. A drug addicted prostitute patient knows something about Eric. A pair of twin brothers, one in a coma, the other having a nervous breakdown, end up in MCW.
- Paul & Merel return from Portugal because she feels her end is near. Tessa challenges Reini's authority by implementing new measures. Selma's pregnant friend Marjan is diagnosed with having a tumor in her breast. Nel is having trouble with Jaap and finds herself attracted to a patient who dreams of a career in music.
- Joy's half brother says he wants to go straight, but Tessa remains skeptical. The Commision reviews the working relationship between Simon and Liza. Alberts is setting a trap for Victor Brouwer and pressures Jan to provide evidence.
- Medisch Centrum West has been forced to fuse with het PolderZiekenhuis, leading to a shortage of beds and a surplus of staff. Selma and Guus look set to lose their jobs. Sonja wants to operate again despite being HIV positive. Reini's estranged sister Vronie has been hospitalized. Nel is facing a divorce from Jaap, who want to emigrate to the States. Paul van der Voort seeks to reinstate Jan van der Wouden, who is currently working as a waiter, at MCW.
- Jan and Eva's baby arrives 2 months ahead of schedule. Eric thinks new intern Bas Strating looks very familiar. Lucy's father returns to stay from Saudi Arabia. Suzanne takes a dislike to a sexist patient called Johan Spoor.
- Evert Smit returns to MCW with a shot wound and a similarly wounded police officer. Eric tries to blackmail De Bak concerning the latter's gambling problems. Irene, now a widow, decides to move to Australia.
- Paul vd Voort has been reinstated at MCW. Nel begins an affair with Robin. Tessa becomes attached to a suicidal man who is HIV positive.
- Simon is suffering heart trouble. Ingrid gives Eva her blessing to begin an affair with Jan. When comatose Adriaan Schapers dies by suffocation, his brother Koos becomes the prime suspect. Eric is supplying patient Patricia Keizer with drugs to keep her quiet. Suzanne has spotted her stalker in MCW and wants Pieter to follow him.
- Eric diagnoses a young mother of three as a hypochondriac, but Jan thinks there might be something else going on. Director Walter de Bak and Dick prefer Eric to replace Paul instead of his preferred choice, Jan.
- When family man Gerrit Hiemstra is taken in with a venereal he admits to being bi-sexual. Suzanne wants her father to turn himself in on account of incest. Eric releases Katrien Wolverton, who promptly starts hyperventilating.
- Dick wants to try out the experimental new medicine CHK on Johan Breeveld. Eva is considering an abortion in favor of her medical career. The still recuperating Simon is confronted by Liza's jealous soon to be ex-husband. Eric threatens to kill himself if Linda won't take him back.
- Alberts is concerned about Brouwer's integrity. Dick is worried about Reini's drinking. Jacob refuses to disclose the ingredients of the experimental medicine he used on Bobby.
- Ingrid has inherited all of Swartjes money, to the dismay of his nephew Sander Hertinga. Chronically ill Antoine Oomen wants to give up on his treatments. Nel finds out her old friend Monica is offering very special help to crippled patient Frans Verwoerden.
- Albert Richter needs a bone marrow transplantation. His son Guido turns out to be incompatible, causing his mother Josephine to make a confession. Antoine goes into a depression during his latest treatment. His father offers to travel to America with him. Eric gets into more trouble when he agrees to help Putman with another money making scheme.
- Astrid wants to stop her son's treatments and take him home. Tessa begins to treat a burn victim. Against all hope, Gerda Dekker awakens from her 8 month coma. Leo Koning opens a fitness center called 'Bubbles' and asks Linda Koning to manage it.
- Paul meets his son Joost and Joost's mother Merel meets Paul's wife Agnes. Jan's school friend Alex is having heart problems. Jan suspects it has less to do with his work than with his down syndrome son.
- Irene has caught her husband Thomas having an affair with Emma, their babysitter. But the others soon suspect there is something else wrong with Irene's health. Liza learns that Simon is using drugs to relax.
- Suzanne is awaiting trial for bashing Johan's head in when he tried to rape Ingrid. Her psychiatrist Vera Zomer tries to get proof Suzanne was the victim of incest when she was young. Bas hacks into the hospital computer and finds out Sonja is HIV positive, which she has been keeping secret.
- Ingrid has had a miscarriage. Thomas Scheltema returns from Gran Canaria to see his ill wife, Irene. Eric's plan to claim he has a great job offer from his father has backfired on him.
- Susan becomes very on edge when her father is brought into MCW. Eric is blackmailing Simon with knowledge of his addiction. Nelleke is fascinated by an ex-trapeze artist patient.
- Liza and Dr. Berghof operate on Simon's heart. Eva and Jan have fallen for each other. Suzanne's stalker has given himself away, but the police still don't take her accusations seriously. Eric confesses his adultery to Ellen.