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1-17 of 17
- The quirky spin on Conan Doyle's iconic sleuth pitches him as a "high-functioning sociopath" in modern-day London. Assisting him in his investigations: Afghanistan War vet John Watson, who's introduced to Holmes by a mutual acquaintance.
- A mature Queen Elizabeth endures multiple crises late in her reign including court intrigues, an assassination plot, the Spanish Armada, and romantic disappointments.
- After finding love, Bridget Jones questions if she really has everything she'd ever dreamed of having.
- Michael Mosley takes an in-depth look at blood. He carries out six experiments on his own blood, from starving it of oxygen to injecting it with snake venom and even eating it.
- Bodies feel heavier when dead. In a dark corridor, a woman struggles with a lozenge-shaped bundle. Larger and heavier than her, she drags it along, finally hauling it upright only to find that she does not have the strength to go on.
- Mysterious symbols and murders are showing up all over London, leading Sherlock and John to a secret Chinese crime syndicate called Black Lotus.
- Mycroft needs Sherlock's help, but a remorseless criminal mastermind puts Sherlock on a distracting crime-solving spree via a series of hostage human bombs through which he speaks.
- War vet Dr. John Watson returns to London in need of a place to stay. He meets Sherlock Holmes, a consulting detective, and the two soon find themselves digging into a string of serial "suicides."
- Invalided home from the war in Afghanistan, Dr. John Watson becomes roommates with the world's only "consulting detective," Sherlock Holmes. Within a day their friendship is forged and several murders are solved.
- Sherlock must confiscate something of importance from a mysterious woman named Irene Adler.
- Jim Moriarty hatches a mad scheme to turn the whole city against Sherlock.
- Mycroft calls Sherlock back to London to investigate an underground terrorist organization.
- Sherlock tries to give the perfect best man speech at John's wedding when he suddenly realizes a murder is about to take place.
- Sherlock goes up against Charles Augustus Magnussen, media tycoon and a notorious blackmailer.
- John and Lestrade try to move on with their lives after Sherlock's apparent death. However, Anderson believes he is still alive.
- In the final chapter the presenters discover what ended The Great Fire and how the city rebuilt itself from the ashes.
- A terrorist attack targets a public school, and an unhappy sniper opens up on Home Secretary Montague.