A prologue summarizing the first three Tarzan films was added to the beginning of the serial.
Kamuela C. Searle was seriously injured during filming. According to the book "Tarzan of the Movies" by Gabe Essoe, Searle died of these injuries. However, other sources state he actually died in 1924.
Jack Hoxie was originally to play Tarzan, but before filming began he pulled out, as he wasn't particularly enthusiastic about playing Tarzan to begin with.
The original plan was to film the production on a tropical island in the South Pacific where they would use the natives as extras.
During the filming at Corona del Mar, the boats "Lady Alice" and "Comfort" replicas were stripped by pirates during the night and no trace of the stolen property was ever found.