The show was a parody of the movie Those Magnificent Men in Their Flying Machines or How I Flew from London to Paris in 25 Hours 11 Minutes (1965).
Unusually for a Hanna-Barbera show, only two voice actors (Paul Winchell and Don Messick) provided all the characters' voices.
The German version had the main characters' names changed to Fliegbert von Sichthofen and Meutrich. In the German dub of 'Wacky Races', their original names were kept.