- Baron Frankenstein, with the aid of a young doctor and his fiancée, kidnaps the mentally sick Dr. Brandt in order to perform the first brain transplant operation.
- Baron Frankenstein travels to a new town to meet Dr. Brandt with whom his has been corresponding and with whom he had hoped to collaborate. He arrives however to learn that Brandt is in a mental institution, having lost his mind completely. He takes a room in a boarding house run by the pretty young Anna who just happens to be engaged to Karl, a doctor who works at the asylum where Dr. Brandt is being kept. When Frankenstein learns that Karl has been stealing drugs, he blackmails him and Anna to work as his assistants. He is desperate to learn a secret that Brandt was going to share with him and kidnaps him with the intent of extracting that secret by transplanting his brain into another body.—garykmcd
- Baron Frankenstein is once again working with illegal medical experiments - brain transplants to keep the most brilliant minds working in new bodies. He has just finished decapitating a physician for his work when a burglar, fleeing a patrolling officer, accidentally lets himself into the baron's lab. The robber is horrified to see the head and flees to tell the police. Frankenstein knows this location is no longer viable and changes to a new city. He forces a young doctor, Karl, and his fiancee Anna to assist him after he catches Karl smuggling drugs from the mental institution where he works for Anna's ailing mother. First, the baron wishes to rescue his fellow researcher, Dr. Brant, who is a patient at the mental institution. He is desperate to learn Brant's secret about preserving brains. Brant is nabbed but is in bad physical shape having suffered a heart attack. He needs a new body immediately. So, the baron eliminates the asylum director, Professor Richter, whose body he can utilize. A nosy police inspector starts to put clues together about missing medical equipment and people who have vanished. His officers nearly stumble on Frankenstein's lab but miss it. When Brant awakes by himself in his new body, he is not thrilled. Neither is his wife when he calls on her. She had already seen his original body in a hidden grave.—Garon Smith
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By what name was Frankenstein Must Be Destroyed (1969) officially released in India in English?
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