This is the first film in the series to be directly affiliated with the 1986 original. There are, however, some glaring inconsistencies. One is that William Katt's character is married to Terri Treas with a 12 year old daughter, with no mention of the fact that he was married to Kay Lenz and had a son in the first film.
This is the only House movie that includes blood. House III: The Horror Show was technically not a part of the series, only being titled House III in certain territories. In some nations, including the United States, that film was released as The Horror Show.
The only sequel in the series to actually be written and conceived as a sequel to the original from the start.
Nowhere in the film is it addressed how wheelchair-bound Laurel is able to get upstairs or the front steps.