The Filmation logo appears with a musical chime, and the "Presents" title is a scrawl rather than in a typeface.
In the title sequence, Prime Evil chases the Ghostbusters, then the Ghostbusters pull out their equipment and chase Prime Evil, and finally the Ghostbusters are chased by the series title and the GB logo.
In the title sequence, as Tracy the Ape swings away from the screen he reveals Lou Scheimer's credit as executive producer (Scheimer was also the voice of Tracy).