Sis is the maid in the Higgins home, adjoining that of Prof. Doolittle, a physical culture specialist. Sis takes up the study of "fysical culture" with disastrous results, for her throwing out of the medicine ball renders the Doolittle maid a subject for hospital treatment. Sis is then loaned to the Professor's establishment. On that night the perfect maid had planned with her pal to get away with the family plate. Sis and the Professor plan an elopement, the Professor's sister and Skull N. Bones, the local undertaker, plan the same thing, the pal arrives to carry out his plan with the maid, and detectives who have beard the maid delirious talk in the hospital, appear to frustrate the scheme. Naturally there is a mix-up of considerable proportions with a goodly share of laughs before matters are straightened out.
—Moving Picture World synopsis