Professor Notty, the naturalist, attempts to sort out his bugs and other flora and fauna, but his wife, the neighbors the ashman, the children in the attic, the iceman, a housecleaning maid, and a boy with a reflecting mirror torment him into a frenzy and he is unable to work. Professor Notty rushes from garret to cellar in his flight to obtain peace and finally runs madly to the local insane asylum and demands admission. He is chased by his family and friends, however, and after he is saved from incarceration is repaid by seeing his tormentors punished.
—Moving Picture World synopsis