The music in the intro movie was performed by Queens of the Stone Age. The songs were originally placeholders by Taylor Kurosaki who is a fan of the band that were intended to be replaced by soundalikes but the licensed music ended up in the final game.
Ratchet from Ratchet and Clank can be also be played in this game by having Ratchet: Deadlocked (2005) in your memory but if is PS4 you need then a Save File of Ratchet and Clank (PS4 game)
The music was composed by various metal bands including A Perfect Circle, Tool, Faith No More, and The Crystal Method.
The developers decided on poison being central to the storyline because the conflict would seem personal.
Rayn originally had a Reubenesque design that resembles her father Krew but the developers later decided to make her beautiful.