The title of this episode --"B.D.O.C." -- is a made-up acronym for the phrase "Big Dick on Campus," which was considered too risqué to spell out in full. It is a parody of the acronym BMOC -- Big Man on Campus -- an unofficial 'title' historically given to popular male college students. As with many other Third Rock episodes, the titles become double entendres based on the use John Lithgow's character name "Dick."
The "pretty boy" alien that Sally hires on sight to take Tommy's place is named Bryce Canyon, an obvious reference to Bryce Canyon National Park in Utah USA.