Sally wants to live on her own. She asks Mary for advice, and when Dick suggests how "frightening" living alone is, Mary says it depends on what the definition of "is" is. This is a direct reference to the Bill Clinton-Monica Lewinsky grand jury testimony the previous year.
Kristen Johnston sounds like she has a cold in this episode.
Harry Solomon, dancing as a baby at the start of the episode, is a parody of the "Dancing Baby" that was popular on the internet during the mid 1990's. It can be found on YouTube.