Here we go with another eccentric "professor." This one is Prof. Van Wick, a man who was looking through his telescope at the time Superman broke an asteroid (an early episode) that was headed to Earth. He noticed Superman getting weak as some strange-glowing metal came out of the asteroid. He was in Africa at the time and saw one of the strange-looking particles fall nearby. It turns out to be Kryptonite and he brings that rock back with him to Metropolis to sell to a gangster for eight million dollars.
Meanwhile, another man. "Gary Allen" (Robert Lowery) who also was in the same vicinity in Africa at the time of the famous explosion, seems to be affected, too, by Kryponite. Just by coincidence, Allen is a friend of Clark Kent's and is on the same plane to Metropolis. The rock, hidden in a suitcase, makes Allen feint when it appears near him at the checkout counter. This happens to Kent, too, who comes to his rescue.
The rest of the story - with, yes, a ton of holes in it - involves how Superman can get rid of that rock, capture the crooks, and save Jimmy and Lois who - for the hundredth time - are taken hostage. Nothing "super," but the usual entertaining show. The crooks, as usual, were dumb and fun to watch and had names like "Big Tom Rufus," "The Snorkel" and "The Dutchess."