At the time this episode takes place, around 1870, there was no cure for leprosy, but with the discovery of penicillin and modern antibiotics, it can now be cured with 6 to 12 months of a multidrug treatment.
Jane Seymour told Entertainment Tonight that she made trips to England herself to acquire authentic period lace for many of the costumes.
The role of Preston Lodge was originally intended for actor Hugh Jackman but fell through.